Document Detail

Predictors of Ischemia in Patients Referred for Evaluation of Exertional Dyspnea: A Stress Echocardiography Study.
MedLine Citation:
PMID:  23098781     Owner:  NLM     Status:  Publisher    
BACKGROUND: There are conflicting data on the incidence of ischemia by stress echocardiography in patients referred for dyspnea without accompanying chest pain. METHODS: A total of 311 consecutive patients with exertional dyspnea (without chest pain) referred to the echocardiography lab for ischemia evaluation from August 2008 to March 2012 were evaluated. Exercise by Bruce protocol or dobutamine stress echocardiography was performed. Resting left ventricular ejection fraction and segmental wall motion abnormalities were assessed. Multivariate logistic regression analysis was used to identify independent predictors of ischemia on stress echocardiography. RESULTS: The mean age was 61 years (range, 20-96 years), with 196 women (63%). Exercise stress was performed in 114 patients (37%); the rest of the patients underwent dobutamine stress. The patient population had a high burden of obesity, diastolic dysfunction, and pulmonary hypertension. Thirty patients (10%) had evidence of stress-induced ischemia (nine [8%] with exercise and 21 [11%] with dobutamine). In multivariate analysis, male gender (odds ratio, 2.8; P = .03), history of coronary artery disease (odds ratio, 3.5; P = .02), and resting wall motion abnormalities (odds ratio, 16.6; P < .01) were independent predictors of inducible ischemia. CONCLUSIONS: The incidence of stress-induced ischemia is low in patients referred for stress echocardiography with exertional dyspnea (without chest pain). Ischemia is more likely to be present in men with histories of coronary artery disease and resting wall motion abnormalities.
Edgar Argulian; Dan G Halpern; Vikram Agarwal; Shiv K Agarwal; Farooq A Chaudhry
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-22
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  -     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.
Division of Cardiology, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians & Surgeons, New York, New York.
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