| Predictors of Acute Bilirubin Encephalopathy Among Nigerian Term Babies with Moderate-to-severe Hyperbilirubinaemia. | |
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MedLine Citation:
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PMID: 20554515 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective: To determine predictors of acute bilirubin encephalopathy (ABE) among term infants presenting with moderate-to-severe hyperbilirubinaemia. Methods: Babies with total serum bilirubin >15 mg/dl at the point of admission were studied in a Nigerian tertiary health facility using bivariate and multivariate analysis. Results: Out of 152 babies, 75 (49.3%) had ABE: 73 had ABE at presentation while two developed ABE after admission. Bivariate analysis showed that body weight <2.5 kg, outside delivery, low maternal education, low socio-economic status, severe anaemia, glucose-6-phosphate dehydrogenase deficiency and metabolic acidosis were significantly associated with ABE. Multivariate analysis also showed that only outside delivery, weight <2.5 kg, presence of severe anaemia and acidosis were the predictors of ABE in this cohort of term babies. Conclusion: The identified predictors of ABE are modifiable and can be used to draw up screening tools for term babies at risk of ABE especially in the developing world. |
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Authors:
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Tinuade A Ogunlesi; Olusoga B Ogunfowora |
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Publication Detail:
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Type: Journal Article Date: 2010-06-15 |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 57 ISSN: 1465-3664 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: England |
Other Details:
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Languages: eng Pagination: 80-6 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu 121001NG, Nigeria. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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