Document Detail


Predictors of Acute Bilirubin Encephalopathy Among Nigerian Term Babies with Moderate-to-severe Hyperbilirubinaemia.
MedLine Citation:
PMID:  20554515     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective: To determine predictors of acute bilirubin encephalopathy (ABE) among term infants presenting with moderate-to-severe hyperbilirubinaemia. Methods: Babies with total serum bilirubin >15 mg/dl at the point of admission were studied in a Nigerian tertiary health facility using bivariate and multivariate analysis. Results: Out of 152 babies, 75 (49.3%) had ABE: 73 had ABE at presentation while two developed ABE after admission. Bivariate analysis showed that body weight <2.5 kg, outside delivery, low maternal education, low socio-economic status, severe anaemia, glucose-6-phosphate dehydrogenase deficiency and metabolic acidosis were significantly associated with ABE. Multivariate analysis also showed that only outside delivery, weight <2.5 kg, presence of severe anaemia and acidosis were the predictors of ABE in this cohort of term babies. Conclusion: The identified predictors of ABE are modifiable and can be used to draw up screening tools for term babies at risk of ABE especially in the developing world.
Authors:
Tinuade A Ogunlesi; Olusoga B Ogunfowora
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Publication Detail:
Type:  Journal Article     Date:  2010-06-15
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  57     ISSN:  1465-3664     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  80-6     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu 121001NG, Nigeria.
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