| Predictors of Active Injection Drug Use in a Cohort of Patients Infected With Hepatitis C Virus. | |
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MedLine Citation:
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PMID: 23153145 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objectives. We investigated potential risk factors for active injection drug use (IDU) in an inner-city cohort of patients infected with hepatitis C virus (HCV). Methods. We used log-binomial regression to identify factors independently associated with active IDU during the first 3 years of follow-up for the 289 participants who reported ever having injected drugs at baseline. Results. Overall, 142 (49.1%) of the 289 participants reported active IDU at some point during the follow-up period. In a multivariate model, being unemployed (prevalence ratio [PR] = 1.93; 95% confidence interval [CI] = 1.24, 3.03) and hazardous alcohol drinking (PR = 1.67; 95% CI = 1.34, 2.08) were associated with active IDU. Smoking was associated with IDU but this association was not statistically significant. Patients with all 3 of those factors were 3 times as likely to report IDU during follow-up as those with 0 or 1 factor (PR = 3.3; 95% CI = 2.2, 4.9). Neither HIV coinfection nor history of psychiatric disease was independently associated with active IDU. Conclusions. Optimal treatment of persons with HCV infection will require attention to unemployment, alcohol use, and smoking in conjunction with IDU treatment and prevention. (Am J Public Health. Published online ahead of print November 15, 2012: e1-e7. doi:10.2105/AJPH.2012.300819). |
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Authors:
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Carrie Reed; Caleb Bliss; Sherri O Stuver; Timothy Heeren; Sheila Tumilty; C Robert Horsburgh; Jeffrey H Samet; Deborah J Cotton |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-15 |
Journal Detail:
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Title: American journal of public health Volume: - ISSN: 1541-0048 ISO Abbreviation: Am J Public Health Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1254074 Medline TA: Am J Public Health Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Carrie Reed, Sherri O. Stuver, and C. Robert Horsburgh Jr are with the Department of Epidemiology, Boston University School of Public Health, Boston, MA. Caleb Bliss and Timothy Heeren are with the Department of Biostatistics, Boston University School of Public Health. Sheila Tumilty and Deborah J. Cotton are with the Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine. Jeffrey H. Samet is with the Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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