Document Detail


Predictive value of the relative lymphocyte count in coronary heart disease.
MedLine Citation:
PMID:  20922539     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The physiological stress suffered by patients with coronary heart disease (CHD) may result in a shift in leukocyte differential toward a decreased percentage of lymphocytes (L%). The purpose of this study was to determine the prognostic value of a low L% in CHD. One hundred forty patients evaluated in our department between 2007 and 2008 were retrospectively reviewed. Thirty-eight patients had primary percutaneous coronary intervention (PCI), and 102 patients had elective PCI. Various statistical analyses were used to examine the association between a low L% or other clinical characteristics and CHD. Univariate analysis showed that low L% was significantly related to ACS compared with stable CHD or control. White blood cell (WBC) count, C-reactive protein (CRP) and left ventricular systolic dysfunction (LVSD) were also correlated with CHD. Multivariate analysis and logistic regression analysis revealed that L%, CRP, WBC count and LVSD were all independently significant risk factors to have predictive value for CHD and 1 year major adverse cardiac events (MACE). A low L% could be used as an independent predictor for ACS on admission and is associated with MACE during clinical follow-up in CHD patients.
Authors:
Chang Bian; Yihua Wu; Yu Shi; Geng Xu; Jianan Wang; Meixiang Xiang; Shaoxiang Weng; Jun Jiang; Ji Ma
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Publication Detail:
Type:  Journal Article     Date:  2010-10-05
Journal Detail:
Title:  Heart and vessels     Volume:  25     ISSN:  1615-2573     ISO Abbreviation:  Heart Vessels     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511258     Medline TA:  Heart Vessels     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  469-73     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, People's Republic of China.
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