Document Detail


Predictive value of obsessive-compulsive personality disorder in antiobsessional pharmacological treatment.
MedLine Citation:
PMID:  9088884     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous reports have stressed the implication of Personality Disorders as predictors of a poorer treatment outcome in Obsessive-Compulsive Disorder (OCD). The aim of this study was to see whether or not Obsessive-Compulsive Personality Disorder in Obsessive-Compulsive Disorder may be predictive for a poorer outcome to antiobsessive pro-serotonergic pharmacological treatment. For this purpose, 30 OCD patients were divided into two groups according to the presence or absence of Obsessive-Compulsive Personality Disorder. Ten-week standardized treatments with oral SRI drugs were given to look for different outcomes between the two groups in Obsessive-Compulsive symptom severity. At the end of the study we found that the presence of Obsessive-Compulsive Personality Disorder, along with the total number of Personality Disorders, did predict poorer response to pharmacological treatment in OCD.
Authors:
P Cavedini; S Erzegovesi; P Ronchi; L Bellodi
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology     Volume:  7     ISSN:  0924-977X     ISO Abbreviation:  Eur Neuropsychopharmacol     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-07-23     Completed Date:  1997-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9111390     Medline TA:  Eur Neuropsychopharmacol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  45-9     Citation Subset:  IM    
Affiliation:
Ospedale San Raffaele, Department of Neuropsychiatric Sciences, University of Milan School of Medicine, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antidepressive Agents, Second-Generation / administration & dosage,  therapeutic use*
Antidepressive Agents, Tricyclic / administration & dosage,  therapeutic use*
Clomipramine / administration & dosage,  therapeutic use*
Female
Fluvoxamine / administration & dosage,  therapeutic use*
Humans
Male
Obsessive-Compulsive Disorder / drug therapy*,  psychology*
Predictive Value of Tests
Psychiatric Status Rating Scales
Chemical
Reg. No./Substance:
0/Antidepressive Agents, Second-Generation; 0/Antidepressive Agents, Tricyclic; 303-49-1/Clomipramine; 54739-18-3/Fluvoxamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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