Document Detail


Predictive value of early maximal exercise test and thallium scintigraphy after successful percutaneous transluminal coronary angioplasty.
MedLine Citation:
PMID:  3155619     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Restenosis of the dilated vessel after percutaneous transluminal coronary angioplasty can be detected by non-invasive procedures but their ability to predict later restenosis soon after a successful angioplasty as well as recurrence of angina has not been assessed. A maximal exercise test and myocardial thallium perfusion scintigraphy were, therefore, performed in 91 asymptomatic patients a median of 5 weeks after they had undergone a technically successful angioplasty. Primary success of the procedure was confirmed by the decrease in percentage diameter stenosis from 64(12)% to 30(13)% as measured from the coronary angiograms and in the trans-stenotic pressure gradient (normalised for mean aortic pressure) from 0.61(0.16) to 0.17(0.09). A clinical follow up examination (8.6(4.9) months later) was carried out in all patients and a late coronary angiogram obtained in 77. The thallium perfusion scintigram showing the presence or absence of a reversible defect was highly predictive for restenosis whereas the exercise test was not. The positive predictive value of an abnormal scintigram was 82% compared with 60% for the exercise test (ST segment depression/or angina or both at peak workload). Angina or a new myocardial infarction occurred in 60% of patients with abnormal and in 21% of patients with normal scintigrams.
Authors:
W Wijns; P W Serruys; M L Simoons; M van den Brand; P J de Feijter; J H Reiber; P G Hugenholtz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  53     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-03-18     Completed Date:  1985-03-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  194-200     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina Pectoris / diagnosis,  therapy*
Angioplasty, Balloon*
Exercise Test*
Female
Follow-Up Studies
Heart / radionuclide imaging*
Humans
Male
Middle Aged
Radioisotopes / diagnostic use*
Recurrence
Thallium / diagnostic use*
Chemical
Reg. No./Substance:
0/Radioisotopes; 7440-28-0/Thallium
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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