Document Detail


Predictive value of coagulation testing in cardiopulmonary bypass surgery.
MedLine Citation:
PMID:  1796727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe postoperative bleeding in cardiopulmonary bypass surgery is still a major problem. One hundred and seven patients undergoing uncomplicated coronary artery bypass grafting (CABG) were studied. Two groups were formed according to the patients' 24 hours postoperative mediastinal blood loss. Patients in group I (n = 70) had blood loss less than 1000 ml and patients in group II (n = 33) had blood loss over 1000 ml. Between the two groups, there were no differences in age, male-female ratio, number of grafts, by pass-time or heparin-protamine dose. Coagulation testing: APTT (Activated Partial Thromboplastin Time), PT (Prothrombin Time), fibrinogen, D-dim. (D-dimers), bleeding time, MPV (mean platelet volume) and platelet count, was done preoperatively (T0), immediately postoperatively (T1), 6 hours postoperatively (T2). We were especially interested in the predictive value of hemostatic parameters at T0 and T1. We found a slight but statistically negative correlation between the platelet count (T0 and T1) and the postoperative blood loss.
Authors:
W Fassin; D Himpe; J P Alexander; S Borms; W Theunissen; P Muylaert; P Van Cauwelaert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  42     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  1991  
Date Detail:
Created Date:  1992-04-09     Completed Date:  1992-04-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  191-8     Citation Subset:  IM    
Affiliation:
Department of Anesthesia and Intensive Care, A.Z.M., Antwerpen.
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MeSH Terms
Descriptor/Qualifier:
Blood Coagulation Tests*
Blood Loss, Surgical
Cardiopulmonary Bypass*
Coronary Artery Bypass*
Female
Hemostasis
Humans
Male
Platelet Function Tests
Postoperative Period
Predictive Value of Tests
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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