Document Detail

Predictive value of abdominal obesity vs. body mass index for determining risk of intensive care unit mortality.
MedLine Citation:
PMID:  20228682     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To explore whether sagittal abdominal diameter as a marker of abdominal obesity is a risk factor for death and morbidity in patients in the intensive care unit and a better outcome determinant for obese patients than body mass index. DESIGN: Prospective, observational study from April 2008 to January 2009. SETTING: Two general intensive care units, both in Toulouse University Hospitals, France. PARTICIPANTS: All adult patients admitted in the two intensive care units except those routinely discharged within 48 hrs or those having conditions with possible effect on anthropometric indices. INTERVENTIONS: Measurement of the sagittal abdominal diameter at admission allowed us to divide the studied population into abdominally obese, underweight, and control groups. MEASUREMENTS AND RESULTS: The primary outcome measure was mortality in the intensive care unit until day 60 after admission. Secondary outcomes were morbidity and length of stay in the intensive care unit. Among 503 patients admitted, 403 were included. At admission, age, diabetes, dyslipidemia, hypertension, Simplified Acute Physiology Score II, and McCabe scores were higher in the abdominally obese group (n = 109) than in the control group (n = 277). The rate of death was higher in the abdominally obese group compared to control (44% vs. 25.3%; p < .01). After adjustment for age, simplified acute physiology score, II and McCabe score, a multivariate analysis showed an increased risk of death in the abdominally obese group (adjusted odds ratio, 2.12; 95% confidence interval, 1.25-3.60). A body mass index >30 kg/m2 was not an independent risk factor for death. During the stay in the intensive care unit, incidence of acute renal failure and abdominal compartment syndrome were higher in the abdominally obese group. CONCLUSION: A high sagittal abdominal diameter, and not a high body mass index, is an independent risk factor of death in critically ill patients.
Jean-Baptiste M Paolini; Julien Mancini; Mich?le Genestal; H?l?ne Gonzalez; Rachel Eshima McKay; Kamran Samii; Olivier A Fourcade
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Critical care medicine     Volume:  38     ISSN:  1530-0293     ISO Abbreviation:  Crit. Care Med.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1308-14     Citation Subset:  AIM; IM    
P?le Anesth?sie et R?animation, Unit?s de R?animation Polyvalente de Purpan et de Rangueil, GRCB 48, IFR 31, Universit? Paul Sabatier, Toulouse, France.
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MeSH Terms
Age Factors
Body Mass Index
Body Weights and Measures / methods*
Health Status
Hospital Mortality
Intensive Care Units
Length of Stay
Middle Aged
Obesity, Abdominal / diagnosis*,  mortality*
Prospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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