| Predictive utility of blood pressure, waist circumference and body mass index for metabolic syndrome in patients with schizophrenia in Singapore. | |
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MedLine Citation:
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PMID: 22747854 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIMS: This study aims to examine and compare the predictive utility of blood pressure (BP), waist circumference (WC) and body mass index (BMI), and to determine optimal cut-off values in prediction of metabolic syndrome (MetS) in patients with chronic schizophrenia. METHODS: About 100 patients with chronic schizophrenia were recruited. BMI and BP were measured and laboratory tests to evaluate patients' high-density lipoprotein cholesterol, triglycerides and glucose levels were performed. Presence of MetS was examined according to AHA/NHLBI guidelines. Predictive utility of BP, WC and BMI was examined using receiver operating curve and discriminant indices were determined accordingly. RESULTS: Forty-six (46%) patients were identified to have MetS. BMI of ≥23 kg m(-2) was most accurate (AUC = 0.83, P < 0.001), with sensitivity of 93.5%, specificity of 48.1%, positive predictive value of 60.6% and negative predictive value of 92.9% in identifying MetS. CONCLUSION: This finding has immediate and significant clinical implications in the local population with schizophrenia. |
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Authors:
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Milawaty Nurjono; Jimmy Lee |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-3 |
Journal Detail:
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Title: Early intervention in psychiatry Volume: - ISSN: 1751-7893 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101320027 Medline TA: Early Interv Psychiatry Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Research Division, Institute of Mental Health, Singapore, Singapore. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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