Document Detail

Predictive significance of magnetic resonance imaging at 4 months of adjusted age in infants after a perinatal neurologic insult.
MedLine Citation:
PMID:  9551187     Owner:  NLM     Status:  MEDLINE    
The aim of this prospective study was to evaluate the predictive significance of magnetic resonance imaging (MRI) performed at 4 months of corrected age in 60 neonates after a perinatal neurologic insult. Follow-up ranged from 2 to 5 years of chronological age. MRI examination was normal in 10; isolated external hydrocephalus was found in 15 infants. Twenty-three of these infants developed normally. Focal or multifocal lesions were shown in 6 infants, of whom 2 developed normally. Diffuse brain involvement was present in 29 cases as atrophy (n = 18), leukomalacia (n = 5), basal ganglia lesions (n = 3), and delayed myelination (n = 3). All but 4 infants showed neurologic impairment. MRI performed at 4 months of adjusted age is of prognostic significance in neonates who suffer a moderate or mild neurologic insult.
V Millet; J M Bartoli; V Lacroze; C Raybaud; D Unal; N Girard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  73     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1998  
Date Detail:
Created Date:  1998-05-08     Completed Date:  1998-05-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  207-19     Citation Subset:  IM    
Neonatal Unit, Hôpital d'Enfants, C.H.U. Timone, Marseille, France.
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MeSH Terms
Basal Ganglia / pathology
Brain Diseases / pathology
Gestational Age*
Hydrocephalus / pathology
Infant, Newborn
Infant, Premature*
Leukomalacia, Periventricular / pathology
Magnetic Resonance Imaging*
Myelin Sheath / physiology
Nervous System Diseases / pathology*
Prospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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