| Predictive risk factors of seizure-related injury in persons with epilepsy. | |
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MedLine Citation:
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PMID: 19520389 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The clinical risk factors for seizure-related injuries (SRI) in adult persons with epilepsy (PWE) were studied and analyzed to develop a predictive model. METHODS: We enrolled 300 consecutive cases from three epilepsy clinics in Northeast, Thailand. Subjects were eligible if reported to have at least one seizure attack during the past 12 months. Face-to-face questionnaire was used to evaluate SRI, baseline characteristics and other seizure-related variables. RESULTS: There were 247 and 91 PWE who met a criterion and had SRI, respectively. By multivariate logistic regression method, GTC seizure type, having history of seizure attacks at least 12 times/year, and daytime seizure were significant risk factors of having SRI with odds ratio of 2.376, 2.460, and 3.562, respectively. We developed the predictive model for having SRI in PWE and it gave 90.3% sensitivity and 46.7% specificity on the occurrence of SRI. The estimated probability of SRI can be found online at http://sribykku.webs.com/. CONCLUSIONS: The significant predictive factors for SRI in PWE were the occurrence of GTCs, seizures at least 12 times/year or daytime seizures. Clinicians or PWE can easily evaluate the risk of having SRI in individuals by the online predictive model. |
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Authors:
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Somsak Tiamkao; Kittisak Sawanyawisuth; Thanin Asawavichienjinda; Prapun Yaudnopakao; Suwanna Arunpongpaisal; Warinthorn Phuttharak; Narong Auevitchayapat; Suda Vannaprasaht; Siriporn Tiamkao; Kutcharin Phunikhom; Aporanee Chaiyakum; Jiamjit Saengsuwan; Suthipun Jitpimolmard |
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Publication Detail:
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Type: Journal Article Date: 2009-06-10 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 285 ISSN: 1878-5883 ISO Abbreviation: J. Neurol. Sci. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-09 Completed Date: 2010-01-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 59-61 Citation Subset: IM |
Affiliation:
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Division of Neurology, Department of Medicine, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. somtia@kku.ac.th |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anticonvulsants / therapeutic use Epilepsy / diagnosis*, drug therapy, epidemiology Female Humans Internet Male Middle Aged Models, Statistical* Photoperiod Questionnaires Risk Factors Seizures / diagnosis*, drug therapy, epidemiology Sensitivity and Specificity Time Factors Wounds and Injuries / diagnosis*, epidemiology, prevention & control Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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