Document Detail

Predictive factors of solid food intake in patients with malignant gastric outlet obstruction receiving self-expandable metallic stents for palliation.
MedLine Citation:
PMID:  22725106     Owner:  NLM     Status:  In-Data-Review    
Aim:  As for self-expandable metallic stents (SEMS) for malignant gastric outlet obstruction (GOO), some predictive factors of stent patency have been reported, although re-canalization of GOO by SEMS does not necessarily lead to favorable food intake. Therefore, we analyzed the predictive factors of oral food intake following SEMS placement. Methods:  A total of 97 consecutive patients in whom SEMS were placed for malignant GOO in five hospitals were included in this retrospective study. Clinical outcomes and predictive factors influencing solid food intake were analyzed. Results:  The technical and clinical success rates were 97.9% and 87.6%, respectively. The mean gastric outlet obstruction scoring system (GOOSS) improved from 0.39 to 2.24 after SEMS placement (P < 0.01). The median eating period was 2.1 months (95% CI, 1.1-3.0 months), and the median survival time was 3.1 months (95% CI, 2.0-4.2 months). A Karnofsky performance status of ≤50 (odds ratio, 3.65; 95% CI, 1.17-13.1; P = 0.03) and ascites (odds ratio, 3.28; 95% CI, 1.23-9.05; P = 0.02) were identified as statistically significant independent poor predictive factors of solid food intake. Conclusion:  SEMS is an effective treatment for patients with malignant GOO. Ascites and a poor performance status were poor predictive factors of solid food intake.
Takashi Sasaki; Hiroyuki Isayama; Yousuke Nakai; Osamu Togawa; Hirofumi Kogure; Kazumichi Kawakubo; Suguru Mizuno; Yoko Yashima; Yukiko Ito; Natsuyo Yamamoto; Naoki Sasahira; Kenji Hirano; Takeshi Tsujino; Nobuo Toda; Minoru Tada; Masao Omata; Kazuhiko Koike
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Publication Detail:
Type:  Journal Article     Date:  2011-11-16
Journal Detail:
Title:  Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society     Volume:  24     ISSN:  1443-1661     ISO Abbreviation:  Dig Endosc     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9101419     Medline TA:  Dig Endosc     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Digestive Endoscopy © 2011 Japan Gastroenterological Endoscopy Society.
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo Department of Gastroenterology, JR Tokyo General Hospital Department of Gastroenterology, Kanto Central Hospital Department of Gastroenterology, Japanese Red Cross Medical Center Department of Gastroenterology, Mitsui Memorial Hospital, Tokyo Yamanashi Prefectural Hospital Organization, Yamanashi, Japan.
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