Document Detail

The predictive value of leukocyte parameters for hypertensive disorders of pregnancy in south China.
MedLine Citation:
PMID:  21962149     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the predictive values of the leukocyte parameters for hypertensive disorders in pregnancy (HDP).
METHODS: A total of 523 HDP patients and 853 normal pregnancies were included in the present study. The leukocyte parameters in different stages of pregnancy were compared among the groups, and the efficiency of clinical diagnosis was calculated to analyze the predictive value of these parameters to HDP.
RESULTS: Women with HDP presented significantly higher leukocyte parameters in the second trimester and significantly lower values in the last trimester as compared to the normal gravidas. An evident increase of several parameters was observed preceding the clinical syndromes of HDP; and the odds ratio of increased neutrophil (NEU) and basophil (Baso) for predicting HDP were 1.02 and 1.16 (p < 0.01), respectively. The sensitivity of NEU was 71.95% when it was higher than 6.12 × 10(9)/L, and the specificity of Baso was 71.01% when it was higher than 0.053 × 10(9)/L for the prediction of HDP in 13-20 weeks.
CONCLUSION: The NEU and Baso are helpful for predicting HDP during the presymptom period.
Hongling Yang; Qian Wang; Wen Tang; Chunyan Zhu; Yanqing Xiao; Jieling Wang
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Publication Detail:
Type:  Journal Article     Date:  2011-09-30
Journal Detail:
Title:  Hypertension in pregnancy     Volume:  31     ISSN:  1525-6065     ISO Abbreviation:  Hypertens Pregnancy     Publication Date:  2012  
Date Detail:
Created Date:  2011-12-21     Completed Date:  2012-04-19     Revised Date:  2014-07-23    
Medline Journal Info:
Nlm Unique ID:  9421297     Medline TA:  Hypertens Pregnancy     Country:  England    
Other Details:
Languages:  eng     Pagination:  11-21     Citation Subset:  IM    
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MeSH Terms
Hypertension, Pregnancy-Induced / blood*
Leukocyte Count*
Predictive Value of Tests
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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