Document Detail

Predictive Risk Factors of Cardiorespiratory Abnormality for Upper Gastrointestinal Endoscopy in Tibet.
MedLine Citation:
PMID:  23314919     Owner:  NLM     Status:  Publisher    
BACKGROUND: To explore the predictive factors of cardiorespiratory abnormality in nonsedated patients at high altitude (HA) during upper gastrointestinal endoscopy (UGIE). METHODS: The pulse and saturated oxygen (SaO(2)) levels of 993 patients undergoing nonsedated UGIE in Tibet were monitored. Bivariate correlation and logistic regression were used to identify predictive risk factors for hypoxemia. RESULTS: The basal and minimum SaO(2) levels during UGIE of the Tibetan group were significantly higher than those of the non-Tibetan group. The minimum SaO(2) and maximum pulse in the HA transient residents groups were significantly higher than those in the HA usual residents groups. The incidences of hypoxemia and severe hypoxemia in the Tibetan groups were significantly lower than those of the non-Tibetan groups. Bivariate correlation and logistic regression showed that race, age (≥40 years), residence time in HA (<10 years), and basal SaO(2) (<89 %) were sufficiently effective to predict hypoxemia. High-risk hypoxemic patients whose residence time in HA was <2 years were more prone to severe hypoxemia. The combination of the four variables showed superior performance in hypoxemia prognosis (AUC-ROC, 0.941; sensitivity, 83.7 %; specificity, 92.5 %) and severe hypoxemia prognosis (AUC-ROC, 0.968; sensitivity, 90.3 %; specificity, 98.0 %). CONCLUSIONS: Race, age, residence time in HA, and basal SaO(2) of patients in HA were predictive variables for hypoxemia during UGIE. Non-Tibetan patients with age ≥40 years, residence time in HA <10 years, and basal SaO(2) <89 % were prone to hypoxemia. Among those groups, patients whose residence time was <2 years were at higher risk for severe hypoxemia.
Feng Liu; Jian-Qiang Liu; Su-Zhi Li; You-Wei Chen; De-Qing Yangzong; Zhao Shen Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-13
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  -     ISSN:  1573-2568     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Gastroenterology, Changhai Hospital, The Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.
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