Document Detail

A Predictive Model Identifies Patients Most Likely to Have Inadequate Bowel Preparation for Colonoscopy.
MedLine Citation:
PMID:  22239959     Owner:  NLM     Status:  Publisher    
BACKGROUND & AIMS: An inadequate level of bowel preparation can affect the efficacy and safety of colonoscopy. Although some factors have been associated with outcome, there is no strategy to identify patients at high risk for inadequate preparation. We searched for factors associated with an inadequate level of preparation and tested the validity of a predictive clinical rule based on these factors. METHODS: We performed a prospective study of 2811 consecutive patients who underwent colonoscopy examinations at 18 medical centers; clinical and demographic data were collected before the colonoscopy. Bowel preparation was classified as adequate or inadequate; 925 (33%) were found to have inadequate preparation. Multivariate analysis was used to identify factors associated with inadequate preparation, which were expressed as odds ratio (OR) and used to build a predictive model. RESULTS: Factors associated with inadequate bowel preparation included being overweight (OR, 1.5), male sex (OR, 1.2), a high body mass index (OR, 1.1), older age (OR: 1.01), previous colorectal surgery (OR, 1.6), cirrhosis (OR, 5), Parkinson disease (OR, 3.2), diabetes (OR, 1.8), and positive results in a fecal occult test (OR, 0.6). These factors predicted which patients would have inadequate cleansing with 60% sensitivity, 59% specificity, 41% positive and 76% negative predictive values; they had an under the receiver operating characteristic curve value of 0.63. Assuming a 100% efficacy of a hypothetical regimen to address patients predicted to be at risk of inadequate preparation, the rate would decrease from 33% to 13%. CONCLUSIONS: We identified factors associated with inadequate bowel preparation for colonoscopy and used these to build an accurate predictive model.
C Hassan; L Fuccio; M Bruno; N Pagano; C Spada; S Carrara; C Giordanino; E Rondonotti; G Curcio; P Dulbecco; C Fabbri; Casa Della; S Maiero; A Simone; F Iacopini; G Feliciangeli; G Manes; A Rinaldi; A Zullo; F Rogai; A Repici
Related Documents :
1977739 - Postural hypotension in chronically medicated schizophrenics.
16182569 - Mental rotation in schizophrenia.
384809 - Immunologic reaction of psychotic patients to fractions of gluten.
7317699 - Cognitive dysfunction in schizophrenia, affective disorder and organic brain disease.
2343749 - Psychopathological characteristics in alcohol hallucinosis and paranoid schizophrenia.
1812499 - Coincidence of schizophrenia and hyperbilirubinemia.
15487959 - The direct thrombin inhibitor melagatran/ximelagatran.
19685419 - The patient with asymptomatic shortened cervix at 23 to 28 weeks: is delivery imminent?
24231779 - Patterns of lumbar disc degeneration are different in degenerative disc disease and dis...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-9
Journal Detail:
Title:  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association     Volume:  -     ISSN:  1542-7714     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160775     Medline TA:  Clin Gastroenterol Hepatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved.
Endoscopy Unit, Humanitas Irccs, Rozzano, Milano.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a populat...
Next Document:  A molecular simulation study of the effects of stationary phase and solute chain length in reversed-...