| Prediction of survival time of rats in severe heat. | |
| | |
MedLine Citation:
|
PMID: 1141103 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The response pattern of the rectal temperature of unanesthetized rats exposed to an acute heat in a room of 42.5 degrees C, rh 40% was analyzed in relation to survival time (S), equilibrium rectal temperature (Te), rise in Te from the initial temperature (Delta Te), and the slope of the changes in rectal temperature during the equilibrium period (Gt). A very wide fluctuation of the survival time (from 46.8 to 250.0 min) was observed between individual rats. For prediction of the survival time, following formula was obtained: log(S) = K1 - K2 times log (Te) - K3 times log (Delta Te) + k4 times 10- minus Gt. K1-4 are constants which differ according to sex. The predicted survival time showed highly constant results in individual rats when measured by repeated exposures. The predicted time coincided well with the survival time actually measured, the difference between the two (measured minus predicted) being 2.2 plus or minus 21.7 min (mean plus or minus SD) IN 77 RATS. There was also a significant correlation between the survival time predicted for acute heat exposure and the actual survival time of individual rats when they were exposed to a chronic heat by daily elevation of the rearing room temperature by 1.0 degrees C. |
| | |
Authors:
|
K Ohara; F Furuyama; Y Isobe |
Related Documents
:
|
10898753 - Mechanism of the alcohol cyclic pattern: role of the hypothalamic-pituitary-thyroid axis. 613333 - In vivo bioelectrochemical changes associated with exposure to extremely low frequency ... 21233343 - Nad(p)h oxidase-derived reactive oxygen species contribute to age-related impairments o... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of applied physiology Volume: 38 ISSN: 0021-8987 ISO Abbreviation: J Appl Physiol Publication Date: 1975 Apr |
Date Detail:
|
Created Date: 1975-09-24 Completed Date: 1975-09-24 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0376576 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 724-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adaptation, Physiological Animals Behavior, Animal / physiology* Body Temperature Regulation* Female Hot Temperature* Male Sex Factors Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Measurement of axial diffusivities in a model of the bronchial airways.
Next Document: Continuous in vivo measurement of arterial PO2 in humans.