Document Detail


Prediction of sudden arrhythmic death following acute myocardial infarction.
MedLine Citation:
PMID:  20610456     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Many patients who survive an acute myocardial infarction (AMI) remain at risk of sudden cardiac death despite optimal medical treatment. AMI survivors are currently risk assessed and selected for implantable cardioverter defibrillator (ICD) insertion mainly on the basis of their left ventricular ejection fraction. Several other cardiovascular tests are available that can detect the myocardial substrate abnormalities and help refine risk. These investigations include ECG-based tests (signal averaged ECG and T-wave alternans), Holter-based recordings (heart rate variability and heart rate turbulence) and imaging techniques (cardiac magnetic resonance). Recent evidence also points towards a potential role for other indices on the 12-lead ECG and genetic profiling in risk prediction. This study reviews the current evidence for the use of these tests in AMI survivors and addresses their pros and cons in guiding the selection of ICD recipients.
Authors:
Reginald Liew
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  96     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-08-16     Revised Date:  2011-06-28    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  1086-94     Citation Subset:  AIM; IM    
Affiliation:
Consultant Cardiologist, National Heart Centre Singapore, 17 Third Hospital Avenue, Singapore. reginald.liew.k.c@nhc.com.sg
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / diagnosis,  etiology*,  prevention & control
Defibrillators, Implantable
Electrocardiography / methods
Electrocardiography, Ambulatory / methods
Humans
Magnetic Resonance Imaging / methods
Myocardial Infarction / complications*
Patient Selection
Comments/Corrections
Comment In:
Heart. 2011 Jun;97(11):949; author reply 949   [PMID:  21558071 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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