| Prediction of restenosis after successful percutaneous coronary angioplasty by dobutamine thallium-201 scintigraphy. | |
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MedLine Citation:
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PMID: 9829332 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated the accuracy of dobutamine thallium-201 myocardial perfusion scintigraphy in predicting restenosis after successful percutaneous coronary angioplasty. Restenosis is one of the most important problems in patients who have undergone percutaneous coronary angioplasty. Exercise thallium-201 myocardial perfusion scintigraphy has been a well accepted non-invasive method to predict the restenosis of the dilated vessel after percutaneous coronary angioplasty, however, the role of thallium-201 myocardial perfusion using dobutamine, as a substitute for exercise in patients unable to exercise, in predicting restenosis is not well known. Therefore, 34 consecutive patients underwent dobutamine tomographic (single photon emission computed tomography) thallium-201 myocardial perfusion scintigraphy following a total of 37 successful angioplasties. No serious side effects during dobutamine infusion occured. The interval between percutaneous coronary angioplasty and scintigraphy ranged between 8 weeks to 2 years. All patients underwent control angiography within one month following myocardial perfusion scintigraphy. Sensitivity, specificity and accuracy of dobutamine myocardial imaging for predicting restenosis were 76%, 79% and 77%, respectively. Sensitivity and specificity related to the vascular territories were: left anterior descending artery 66-69%, left circumflex artery 75-100%, right coronary artery 83-66%, respectively. In conclusion, our findings demonstrating high accuracy of dobutamine myocardial single photon emission tomography for angiographic restenosis suggest its usefulness as a non-invasive tool in the follow-up of percutaneous coronary angioplasty patients. |
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Authors:
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B Caner; A Oto; K Ovunc; P Kiratli |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of cardiology Volume: 66 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1999-01-21 Completed Date: 1999-01-21 Revised Date: 2006-07-12 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 175-81 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Hacettepe University Medical Faculty, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary* Cardiotonic Agents / diagnostic use* Coronary Angiography Coronary Disease / therapy, ultrasonography* Dobutamine / diagnostic use* Female Humans Male Middle Aged Predictive Value of Tests Recurrence Sensitivity and Specificity Thallium Radioisotopes / diagnostic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Cardiotonic Agents; 0/Thallium Radioisotopes; 34368-04-2/Dobutamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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