| Prediction of recovery time from hypoglycemia in patients with insulin overdose. | |
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MedLine Citation:
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PMID: 21519152 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Insulin overdose results in prolonged hypoglycemia. We hypothesized that if a huge amount of insulin is subcutaneously injected, the duration of hypoglycemia depends on the dose of insulin rather than the type of insulin. We conducted a literature review of insulin overdose and 33 cases were included in this study. We assessed the correlation between recovery time from hypoglycemia and insulin dose. As a result, there was a significant correlation between recovery time from hypoglycemia and insulin dose (r = 0.88, p <0.0001) and this correlation was expressed as y = 0.045x; where y is time (h) and x is insulin dose (U), corresponding to that if 1000 U insulin is injected, hypoglycemia will persist for (~)45 h. This equation may be useful to predict the duration of glucose supplementation for treatment of insulin overdose. |
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Authors:
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Takako Ohyama; Yoshifumi Saisho; Ayako Muraki; Toshihide Kawai; Hiroshi Itoh |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-26 |
Journal Detail:
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Title: Endocrine journal Volume: - ISSN: 1348-4540 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9313485 Medline TA: Endocr J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Internal Medicine, Keio University School of Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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