Document Detail


Prediction of progression of radiographic knee osteoarthritis using tibial trabecular bone texture.
MedLine Citation:
PMID:  21989629     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE.: To develop a system for prediction of progression of radiographic knee osteoarthritis (OA) using tibial trabecular bone (TB) texture. METHODS.: We studied 203 knees with (n=68) or without (n=135) radiographic tibiofemoral OA in 105 subjects (90 men, 15 women, mean age 54 years) who had 2 sets of knee radiographs taken 4 years apart. We determined medial and lateral compartment tibial TB texture using an automated region selection method. Three texture parameters were calculated: roughness, degree of anisotropy, and direction of anisotropy based on a signature dissimilarity measure method. We evaluated tibiofemoral OA progression using a radiographic semi-quantitative outcome: an increase in the medial joint space narrowing (JSN) grade. We examined the predictive ability of TB texture in knees with and without pre-existing radiographic OA, with adjustment for age, sex, and body mass index using logistic regression (generalized estimating equations) and receiver operating characteristic curves. RESULTS.: The prediction of increased medial JSN in knees with or without pre-existing radiographic OA was the most accurate for medial TB texture; area under the curve (AUC) was 0.77 and 0.75, respectively. For lateral TB texture, AUC was 0.71 and 0.72, respectively. CONCLUSION.: We have developed a system, based on analyzing tibial TB texture, which yields good prediction of loss of tibiofemoral joint space. The predictive ability of the system needs to be further validated. © 2011 American College of Rheumatology.
Authors:
T Woloszynski; P Podsiadlo; G W Stachowiak; M Kurzynski; L S Lohmander; M Englund
Related Documents :
21629469 - Treatment of periprosthetic femoral fractures in hip arthroplasty.
23716039 - Effect of increased fruit and vegetable consumption on bone turnover in older adults: a...
11046159 - From the rsna refresher courses. radiological society of north america. adult chronic h...
19277649 - Radiologic measurement of lesser trochanter and its clinical significance in chinese.
21886009 - Anterior cruciate ligament recostruction with bone-patellar tendon-bone autograft in ta...
22687479 - Topical astragaloside iv-releasing hydrogel improves healing of skin wounds in vivo.
25044359 - Unzipping of small diameter stents: an in vitro study.
14756649 - Deep plane fixation in integumental surgery.
23089559 - Fat mass influence on bone mass is mediated by the independent association between lean...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-11
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  -     ISSN:  1529-0131     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 by the American College of Rheumatology.
Affiliation:
School of Mechanical and Chemical Engineering, University of Western Australia, Crawley, Perth, Western Australia. tom@mech.uwa.edu.au.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Regulation of microglia effector functions by tumor necrosis factor signaling.
Next Document:  Synthesis, structures and stabilities of thioanisole-functionalised phosphido-borane complexes of th...