Document Detail

Prediction of preterm labour in multiple pregnancies.
MedLine Citation:
PMID:  9930289     Owner:  NLM     Status:  MEDLINE    
Various methods of predicting preterm labour in both singleton and multiple pregnancies have been studied including risk scoring systems, home uterine activity monitoring, cervical assessment and biochemical methods. In practice, risk scoring systems for preterm delivery perform poorly. Consensus in the literature regarding the usefulness of home uterine activity monitoring is lacking and well designed randomized controlled trials are required. Transvaginal ultrasound assessment of the cervix appears to have a role to play in the prediction of preterm labour. The presence of IFN in cervicovaginal fluid in the late second and early third trimesters is an important risk factor for preterm labour in asymptomatic women with multiple pregnancies. Preterm labour may be mediated in part by inflammatory cytokines. The measurement of these inflammatory cytokines in cervical secretions may also prove helpful in the prediction of preterm labour. It is anticipated that an improved ability to predict preterm labour in both singleton and multiple pregnancies will depend on increasing understanding of the condition's pathophysiology.
F N Chuileannáin; S Brennecke
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Baillière's clinical obstetrics and gynaecology     Volume:  12     ISSN:  0950-3552     ISO Abbreviation:  Baillieres Clin Obstet Gynaecol     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1999-02-18     Completed Date:  1999-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8710782     Medline TA:  Baillieres Clin Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  53-66     Citation Subset:  IM    
Department of Perinatal Medicine, Royal Women's Hospital, Melbourne, Victoria, Australia.
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MeSH Terms
Cervix Uteri
Extraembryonic Membranes / chemistry
Fetal Membranes, Premature Rupture
Fibronectins / analysis
Home Care Services
Obstetric Labor, Premature / diagnosis*
Physical Examination
Pregnancy Complications, Infectious / etiology
Pregnancy, Multiple*
Prenatal Diagnosis / methods
Risk Assessment
Uterine Contraction
Reg. No./Substance:

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