Document Detail

Prediction of operative cholangiography in patients undergoing elective cholecystectomy with routine liver function chemistries.
MedLine Citation:
PMID:  4012608     Owner:  NLM     Status:  MEDLINE    
A retrospective reviews of 195 consecutive patients who underwent elective cholecystectomy and operative cystic duct cholangiography (OCDC) were reviewed to establish criteria to correlate the preoperative laboratory data of liver chemistry tests and the actual biliary tract disease found in each patients. Patients who had a history of jaundice or other clinical indication for common bile duct exploration were excluded from this study. The patients were divided into four groups based on the results of the OCDC: I negative, II false positive, III false negative, and IV positive for choledocholithiasis. The results of the preoperative liver chemistry studies of the patients in each of the four groups were analyzed by the chi 2 method. The four liver chemistry tests were lactate dehydrogenase, SGOT, bilirubin, and alkaline phosphatase. When results of all preoperative liver chemistry tests were normal, there was no incidence of choledocholithiasis. As the number of chemistry test result elevations increased from one to four, the incidence of choledocholithiasis increased from 17% to 50% (p less than 0.001). Preoperative liver chemistry tests in selected patients undergoing elective cholecystectomy may provide a valuable indicator to the surgeon as to whether an OCDC should be performed at the time of surgery.
P Del Santo; K K Kazarian; J F Rogers; P A Bevins; J R Hall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  98     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-08-09     Completed Date:  1985-08-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  7-11     Citation Subset:  AIM; IM    
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MeSH Terms
Alkaline Phosphatase / blood
Aspartate Aminotransferases / blood
Bilirubin / blood
Cholangiography / methods*
Cholelithiasis / radiography*
Gallstones / radiography*
Intraoperative Period
L-Lactate Dehydrogenase / blood
Preoperative Care
Reg. No./Substance:
635-65-4/Bilirubin; EC Dehydrogenase; EC Aminotransferases; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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