Document Detail


Prediction of mortality and the need for neonatal extracorporeal membrane oxygenation therapy by 3-dimensional sonography and magnetic resonance imaging in fetuses with congenital diaphragmatic hernias.
MedLine Citation:
PMID:  23716519     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objectives- To compare different rotation angles for assessment of fetal lung volume by 3-dimensional (3D) sonography with magnetic resonance imaging (MRI) regarding prediction of mortality and the need for neonatal extracorporeal membrane oxygenation (ECMO) therapy in fetuses with congenital diaphragmatic hernias. Methods- One hundred patients with fetal congenital diaphragmatic hernias between 22 and 39 weeks' gestation were examined by 3D sonography and MRI. Sonographic contralateral fetal lung volumes were assessed by the rotational technique (virtual organ computer-aided analysis) at 3 different rotation angles: 6°, 15°, and 30°. The MRI fetal lung volumes were calculated based on multiplanar T2-weighted MRI. To eliminate the influence of gestational age, the observed to expected contralateral fetal lung volume on sonography and the observed to expected fetal lung volume on MRI were calculated. Receiver operating characteristic (ROC) curves were calculated for the statistical prediction of survival and need for ECMO therapy by the observed to expected contralateral fetal lung volume (sonography) and observed to expected fetal lung volume (MRI). Results- One hundred cases were assessed for survival and 89 for ECMO necessity (11 neonates were not eligible for ECMO). For prediction of postpartum survival and ECMO necessity, the areas under the ROC curves (AUCs) showed very similar results for MRI and 3D sonography: observed to expected fetal lung volume by MRI, 0.819 (95% confidence interval, 0.730-0.909) and 0.835 (0.748-0.922), respectively; 6° sonography, 0.765 (0.647-0.883) and 0.820 (0.734-0.905); 15° sonography, 0.784 (0.672-0.896) and 0.811 (0.719-0.903); and 30° sonography, 0.732 (0.609-0.855) and 0.772 (0.671-0.872). Comparisons between the AUCs revealed no statistical differences. Conclusions- We have shown the good prognostic value of 3D sonography in fetuses with congenital diaphragmatic hernias compared with MRI, particularly when using small rotation angles. Therefore, it can be an appropriate diagnostic tool when counseling patients for congenital diaphragmatic hernias.
Authors:
Sven Kehl; Leonie Becker; Sven Eckert; Christel Weiss; Thomas Schaible; K Wolfgang Neff; Jörn Siemer; Marc Sütterlin
Related Documents :
24089909 - 4d ct lung ventilation images are affected by the 4d ct sorting method.
20118739 - Osteonecrosis of the tibial plateau: magnetic resonance imaging appearances with quanti...
24900059 - Value of surveillance (18)f-fdg pet/ct in colorectal cancer: comparison with convention...
15468369 - Tenascin-c concentration in synovial fluid correlates with radiographic progression of ...
22951299 - Chest ct in infants and children.
11817479 - Knee imaging after anterior cruciate ligament reconstruction.
15039179 - Pretransplantation diagnosis and staging of hepatocellular carcinoma in patients with c...
7256519 - Superior sagittal sinus thrombosis diagnosed by computed tomography.
7656519 - Mri t staging of squamous cell carcinoma of the oral cavity: radiological-pathological ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  32     ISSN:  1550-9613     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  981-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Mannheim University Medical Center, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany. sven.kehl@gmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Increasing the detection rate of congenital heart disease during routine obstetric screening using c...
Next Document:  The petrous portion of the temporal bone as shown on sonography between 14 and 40 weeks' gestation.