| Prediction of malignancy using transvaginal color flow Doppler in patients with gynecologic tumors. | |
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MedLine Citation:
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PMID: 11578358 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Eighty-five patients referred to the Women's Cancer Center, University of Minnesota had transvaginal color flow Doppler performed to determine if pelvic malignancy could be predicted by blood flow assessment. Their mean age was 49 years (range 21-86 years). Thirty-five patients were subsequently found to have malignant tumors of the cervix, uterus or ovary. The presence of increased intratumoral blood flow as depicted by color flow Doppler had a sensitivity of 83%, specificity of 100%, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 89% for malignancy. The mean intratumoral Pulsatility Index (PI) of the patients with malignant tumors was 0.81 (SD 0.24; range 0.3-1.2), which was significantly lower than for the benign group (P = 0.001). A PI of </= 1.0 had a sensitivity of 96.3%, specificity of 94.3%, PPV of 89.7% and NPV of 98% for predicting malignancy. Transvaginal color flow Doppler shows promise as a method of predicting malignancy in patients with gynecologic pathology. |
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Authors:
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J.R. Carter; J.M. Fowler; J.W. Carlson; L.F. Carson; L.L. Adcock; L.B. Twiggs |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society Volume: 3 ISSN: 1525-1438 ISO Abbreviation: Int. J. Gynecol. Cancer Publication Date: 1993 Sep |
Date Detail:
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Created Date: 2001-Oct-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9111626 Medline TA: Int J Gynecol Cancer Country: - |
Other Details:
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Languages: ENG Pagination: 279-284 Citation Subset: - |
Affiliation:
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Women's Cancer Center, Department of Obstetrics and Gynecology, University of Minnesota, Box 395 Mayo Memorial Building, Minneapolis, MN 55455, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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