| Prediction of left ventricular dilatation with thallium-201 SPET imaging after primary angioplasty in patients with acute myocardial infarction. | |
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MedLine Citation:
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PMID: 12029545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Progressive ventricular dilatation is an important prognostic factor in patients with acute myocardial infarction. We evaluated clinical, angiographic, echocardiographic and thallium-201 single-photon emission tomography (SPET) imaging variables predictive of the change in left ventricular volume during a 7-month follow-up period after primary angioplasty in patients with acute myocardial infarction. Thirty-six patients with first acute myocardial infarction treated with primary angioplasty within 12 h of onset underwent 201Tl SPET imaging (5.8+/-2.1 days after angioplasty). Changes in left ventricular volume were assessed over the 7-month period. The left ventricle dilated significantly after angioplasty ( P<0.001). Multivariate analysis revealed that the number of segments with 201Tl uptake <40% of peak activity was a single independent predictor of increase in end-diastolic volume index between 1 week and 7 months ( R2=0.41, P< 0.001). The presence of two or more segments with 201Tl uptake <40% predicted an increase in end-diastolic volume index of > or =6 ml/m2 with positive and negative predictive values of 85% (17/20) and 75% (12/16), respectively. It is concluded that, following primary angioplasty in patients with acute myocardial infarction, the extent of myocardial infarction assessed by 201Tl SPET can identify those who will develop ventricular dilatation during the subsequent 7 months. |
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Authors:
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Joon Young Choi; Dae Hyuk Moon; Cheol Whan Lee; Jung Woo Shin; Seong-Wook Park; Myeong-Ki Hong; Jae-Kwan Song; Seung-Jung Park; Hee Kyung Lee |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article Date: 2002-04-06 |
Journal Detail:
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Title: European journal of nuclear medicine and molecular imaging Volume: 29 ISSN: 1619-7070 ISO Abbreviation: Eur. J. Nucl. Med. Mol. Imaging Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-05-24 Completed Date: 2003-01-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101140988 Medline TA: Eur J Nucl Med Mol Imaging Country: Germany |
Other Details:
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Languages: eng Pagination: 728-34 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Angioplasty* Dilatation, Pathologic / radionuclide imaging* Female Follow-Up Studies Heart Ventricles / physiopathology, radionuclide imaging Humans Male Middle Aged Myocardial Infarction / diagnosis, radionuclide imaging*, surgery* Observer Variation Postoperative Period Predictive Value of Tests Reproducibility of Results Single-Blind Method Stroke Volume Thallium / diagnostic use* Tomography, Emission-Computed, Single-Photon Ventricular Remodeling |
| Chemical | |
Reg. No./Substance:
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7440-28-0/Thallium; 7791-12-0/thallium chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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