| Prediction of language and neurologic recovery after cerebral infarction with SPECT imaging using N-isopropyl-p-(I 123) iodoamphetamine. | |
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MedLine Citation:
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PMID: 2786406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fourteen patients (10 with left-sided and 4 with right-sided cerebral infarction) were prospectively studied with single-photon emission computed tomography (SPECT) using N-isopropyl-p-(I 123) iodoamphetamine (IMP, SPECTamine) to determine its usefulness in predicting neurologic/language recovery after cerebral infarction. All neuro-SPECT imaging was performed within 30 days after infarction. Detailed assessment of neurologic and/or language recovery (after 3 months) was carried out prospectively in each patient. Patients with smaller volume IMP defects in the region of infarction demonstrated significantly better neurologic and language recovery than patients with large IMP defects. Analysis of the IMP "redistribution" phenomenon failed to demonstrate definitively a relationship with clinical recovery. It was concluded that the volume of the IMP defect can aid in predicting recovery potential after cerebral infarction. |
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Authors:
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D L Bushnell; S Gupta; A G Mlcoch; W E Barnes |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Archives of neurology Volume: 46 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1989 Jun |
Date Detail:
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Created Date: 1989-07-07 Completed Date: 1989-07-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 665-9 Citation Subset: AIM; IM |
Affiliation:
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Nuclear Medicine Service, Hines Veterans Administration Hospital, IL 60141. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Amphetamines / diagnostic use* Brain / radionuclide imaging Cerebral Infarction / physiopathology*, radionuclide imaging Female Forecasting Humans Iodine Radioisotopes / diagnostic use Iofetamine Language* Male Middle Aged Nervous System / physiopathology* Tomography, Emission-Computed* |
| Chemical | |
Reg. No./Substance:
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0/Amphetamines; 0/Iodine Radioisotopes; 95896-48-3/Iofetamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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