Document Detail


Prediction of improved liver function after balloon- occluded retrograde transvenous obliteration: the relation to hepatic vein pressure gradient.
MedLine Citation:
PMID:  21722180     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background and aims Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx) as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the changes of HVPG and liver function. Patients and methods B-RTO was performed in 30 patients with GVx and hepatic encephalopathy. HVPG was measured in 19 of 30 patients both before and after B-RTO. Results The B-RTO was successful in all patients. The GVx and hepatic encephalopathy were improved, and no recurrence and no bleeding were observed within the follow- up period. The serum albumin and prothrombin activity were significantly improved between pre and 6months after B-RTO in all patients. HVPG was elevated 44% above the baseline after B-RTO. The liver function significantly improved 6 months after B-RTO in the patients whose HVPG increased ≥20% from baseline. Conclusion An elevated HVPG after B-RTO is one aspect of the effect for liver function, and an HVPG increase of ≥20% from baseline is a predictive factor for obtaining an improvement of the liver function.
Authors:
Hideo Uehara; Tomohiko Akahoshi; Morimasa Tomikawa; Nao Kinjo; Naotaka Hashimoto; Yoshihiro Nagao; Masahiro Kamori; Yoshihiko Maehara
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-1
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  -     ISSN:  1440-1746     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
Affiliation:
Department of Surgery and Science, Graduate School of Medical Science, Kyushu University 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
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