| Prediction of improved liver function after balloon- occluded retrograde transvenous obliteration: the relation to hepatic vein pressure gradient. | |
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MedLine Citation:
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PMID: 21722180 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background and aims Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx) as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the changes of HVPG and liver function. Patients and methods B-RTO was performed in 30 patients with GVx and hepatic encephalopathy. HVPG was measured in 19 of 30 patients both before and after B-RTO. Results The B-RTO was successful in all patients. The GVx and hepatic encephalopathy were improved, and no recurrence and no bleeding were observed within the follow- up period. The serum albumin and prothrombin activity were significantly improved between pre and 6months after B-RTO in all patients. HVPG was elevated 44% above the baseline after B-RTO. The liver function significantly improved 6 months after B-RTO in the patients whose HVPG increased ≥20% from baseline. Conclusion An elevated HVPG after B-RTO is one aspect of the effect for liver function, and an HVPG increase of ≥20% from baseline is a predictive factor for obtaining an improvement of the liver function. |
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Authors:
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Hideo Uehara; Tomohiko Akahoshi; Morimasa Tomikawa; Nao Kinjo; Naotaka Hashimoto; Yoshihiro Nagao; Masahiro Kamori; Yoshihiko Maehara |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-1 |
Journal Detail:
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Title: Journal of gastroenterology and hepatology Volume: - ISSN: 1440-1746 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Department of Surgery and Science, Graduate School of Medical Science, Kyushu University 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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