| Prediction of fractures in perimenopausal women: a comparison of dual energy x ray absorptiometry and broadband ultrasound attenuation. | |
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MedLine Citation:
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PMID: 8712866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To consider whether bone mineral density (BMD) measurements can predict traumatic fractures occurring in perimenopausal women. METHODS: One thousand perimenopausal women called up for screening underwent both dual energy x ray absorptiometry (DXA) of the spine and hip, and broadband ultrasound attenuation (BUA) of the heel. Two years later, they were sent a questionnaire to discover those who had since had a fracture, and compare them with those who had not. RESULTS: About 2% of the women had sustained a fracture in the two years since attendance for screening. Fractures in this age group can be predicted weakly, but significantly, by bone mass measurements using DXA and BUA (odds ratios from 1.4 to 2.1). The lumbar spine appeared to be one of the best predictive sites (odds ratio for 1 SD reduction in BMD 2.1 (95% confidence interval 1.2 to 3.8)), but no significant differences were found between the areas under the curve in receiver operator characteristic (ROC) analysis. CONCLUSION: In this preliminary study it appeared that bone mass measurements are predictive of perimenopausal traumatic fractures in addition to postmenopausal fractures related to osteoporosis. DXA of the lumbar spine did not perform significantly better than BUA. The number of fractures occurring was low, however, and further long term follow up is required to confirm the finding. |
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Authors:
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A Stewart; D J Torgerson; D M Reid |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of the rheumatic diseases Volume: 55 ISSN: 0003-4967 ISO Abbreviation: Ann. Rheum. Dis. Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-09-09 Completed Date: 1996-09-09 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372355 Medline TA: Ann Rheum Dis Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 140-2 Citation Subset: IM |
Affiliation:
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Osteoporosis Research Unit, Aberdeen Royal Hospitals, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon Accidents Bone Density / physiology* Female Fractures, Bone / prevention & control* Heel / ultrasonography Hip Joint Humans Lumbar Vertebrae / physiology Middle Aged Predictive Value of Tests Premenopause / physiology* |
| Comments/Corrections | |
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