| Prediction of early pregnancy outcomes. | |
| | |
MedLine Citation:
|
PMID: 8582515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: A prospective study was performed on the conception hormones of early pregnancy in order to examine their sensitivity and predictability for early pregnancy loss. METHODS: The serum levels of progesterone, estradiol and human chorionic gonadotropin (hCG) were measured and analyzed at 5-8 weeks of gestation in pregnancies occurring both with and without ovarian stimulation. RESULTS: If a level of < 10 ng/ml of progesterone was chosen as the cut-off value for the prediction of early pregnancy loss, the sensitivity and specificity were 56% and 98%, respectively. The optimal cut-off value was chosen at < 0.5 multiples of the median (MoM) and < 0.4 MoM for estradiol and hCG, respectively. This gave a sensitivity of 80% for estradiol and 85% for hCG, and a specificity of 93% for estradiol and 81% for hCG at week 8 of gestation. CONCLUSION: The combined determination of conception hormones is an efficacious method of monitoring early pregnancy and may be used for predicting outcome. |
| | |
Authors:
|
Y S Lin; C H Liu |
Related Documents
:
|
1110475 - Pregnancy-terminating effect of human chorionic gonadotrophin in rats. 9649085 - Elevated maternal serum relaxin concentrations throughout pregnancy in singleton gestat... 10719325 - Maternal midtrimester serum afp and free beta-hcg levels in in vitro fertilization twin... 22683095 - Men's experiences of antenatal screening: a metasynthesis of the qualitative research. 18753755 - Successful management of pregnancy with nephrotic syndrome due to preexisting membranou... 12752075 - Feasibility of simultaneous application of fetal electrocardiography and fetal pulse ox... |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 51 ISSN: 0020-7292 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 1995 Oct |
Date Detail:
|
Created Date: 1996-03-18 Completed Date: 1996-03-18 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: IRELAND |
Other Details:
|
Languages: eng Pagination: 33-8 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, Tainan, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chorionic Gonadotropin
/
blood* Estradiol / blood* Female Gestational Age Humans Monitoring, Physiologic Predictive Value of Tests Pregnancy Pregnancy Outcome* Progesterone / blood* Prospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Chorionic Gonadotropin; 50-28-2/Estradiol; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Placenta previa and previous cesarean section.
Next Document: A comparison of three tests for determining fetal pulmonary maturity.