| Prediction of ductus arteriosus closure by neonatal screening echocardiography. | |
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MedLine Citation:
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PMID: 15529905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: We reported the incidence, clinical manifestations and outcome of patent ductus arteriosus (PDA) in full-term infants by screening echocardiography. METHODS AND RESULTS: Total 1230 infants received echocardiographic screening and periodic follow-up. On the third day of life, there were 109 infants with isolated ductus arteriosus aneurysm (DAA), those with persistent patency of the ductus arteriosus (DA) in 26. The DA closed within 48 h in 828 infants, and persisted beyond 48 h in 180. The incidence of PDA in full-term infants was 0.91, 0.83 and 0.66% at 1, 4 and 6 months follow-up, and 0.82, 0.73 and 0.64% if infants with DAA were excluded. Infants with PDA had lower birth body weight (BBW) than those with closed DA (p = 0.02). The DA width on the third day of life ranged from 0.23 to 0.43 cm (0.32+/-0.08 cm) and 0.08 to 0.44 cm (0.16+/-0.06 cm) in infants with or without PDA, respectively, which was significantly different (p < 0.05). The sensitivity, specificity, predictive positive and negative values were 87.5, 92.5, 36.8 and 99% respectively for the cuff-off point at 0.25 cm of DA width. CONCLUSIONS: Risk factors in infants with PDA included lower BBW and larger measured DA width at the third day of life. We predicted the arterial duct would close if DA width <0.25 cm, and suggested follow up earlier if >0.25 cm on the third day of life. |
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Authors:
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Sheng-Ling Jan; Betau Hwang; Yun-Ching Fu; Ching-Shiang Chi |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The international journal of cardiovascular imaging Volume: 20 ISSN: 1569-5794 ISO Abbreviation: Int J Cardiovasc Imaging Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-11-08 Completed Date: 2005-09-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100969716 Medline TA: Int J Cardiovasc Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 255-62 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan. sljan@vghtc.gov.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Surgical Procedures* Coronary Circulation / physiology Ductus Arteriosus, Patent / epidemiology, surgery*, ultrasonography* Echocardiography, Doppler, Color* Female Follow-Up Studies Heart Rate / physiology Humans Incidence Infant Welfare Infant, Newborn Male Neonatal Screening / methods* Predictive Value of Tests Prospective Studies Sensitivity and Specificity Sex Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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