Document Detail

Prediction of change in mitral valve area after mitral balloon commissurotomy using cine computed tomography.
MedLine Citation:
PMID:  7995701     Owner:  NLM     Status:  MEDLINE    
RATIONALE AND OBJECTIVES: Mitral balloon commissurotomy (MBC) can successfully increase the mitral valve area (MVA) in mitral stenosis, but the outcome is variable. In multicenter studies, qualitative echocardiographic scores obtained before MBC are only weakly predictive of the increase in MVA after MBC. METHODS: To evaluate whether the change in MVA after MBC can be predicted by evaluating mitral valve morphology using cine computed tomography (CT), we studied 12 women with mitral stenosis and 11 female control subjects. RESULTS: In the patients with mitral stenosis, MVA increased from 1.13 +/- 0.24 to 1.93 +/- 0.56 cm2 (P < .0001) after MBC. A standard echocardiographic score assessment of mitral valve morphology before MBC was not associated with the change in MVA after MBC in these patients (P > .20). However, the total mitral valve morphology score evaluated by cine computed tomography was strongly associated with the change in MVA after MBC (r = -.87; P < .0005). In addition, the individual morphologic characteristics of mitral valve mobility (P < .0025), leaflet thickness (P < .05), and subvalvular disease (P < .05) were significant predictors of the change in MVA after MBC. CONCLUSION: Cine computed tomography may be useful for predicting immediate increases in MVA in patients after MBC and may be helpful for preoperative assessment of these patients.
M L White; M Grover-McKay; R M Weiss; B F Vandenberg; T L Burns; M D Winniford; W Stanford; C R McKay
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Investigative radiology     Volume:  29     ISSN:  0020-9996     ISO Abbreviation:  Invest Radiol     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-01-19     Completed Date:  1995-01-19     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0045377     Medline TA:  Invest Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  827-33     Citation Subset:  IM    
Department of Internal Medicine, University of Iowa, Iowa City.
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MeSH Terms
Balloon Dilatation*
Echocardiography, Doppler
Middle Aged
Mitral Valve / physiopathology,  radiography*
Mitral Valve Stenosis / physiopathology,  radiography*,  therapy*,  ultrasonography
Observer Variation
Radiography, Interventional*
Tomography, X-Ray Computed*

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