| Prediction of benign and malignant endometrial disease: hysterosonographic-pathologic correlation. | |
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MedLine Citation:
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PMID: 10207420 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the transvaginal hysterosonographic appearances of benign and malignant endometrial disease. MATERIALS AND METHODS: From April 11, 1994, through August 1, 1996, a total of 88 women (age range, 25-81 years) underwent transvaginal hysterosonography and histopathologic evaluation of the endometrium after dilation and curettage or after hysterectomy. A benign appearance at transvaginal hysterosonography was defined as a thin endometrium, diffuse smooth endometrial thickening, or a smoothly marginated, homogeneously echogenic, pedunculated endoluminal mass. A suspicious appearance was defined as either irregular thickening of the endometrium or an inhomogeneous endoluminal mass. RESULTS: Of 88 women, 37 had a benign-appearing endometrium at transvaginal hysterosonography; at histologic examination, 16 had a proliferative endometrium, 12 had a secretory endometrium, six had polyps, two had an inactive endometrium, and one had carcinoma. Of the 51 women with suspicious endometrial appearances, eight had carcinoma, 24 had adenomatous polyps, five had hyperplasia, 11 had fibroids, and three had endometritis. For carcinoma, the sensitivity of transvaginal hysterosonography was 89%, specificity was 46%, positive predictive value was 16%, and negative predictive value was 97%. CONCLUSION: A thin endometrium or diffuse smooth endometrial thickening is predictive of benign endometrial histologic findings, but all women with endoluminal masses require further histologic evaluation to exclude malignant disease. |
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Authors:
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T J Dubinsky; K Stroehlein; Y Abu-Ghazzeh; H R Parvey; N Maklad |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 210 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1999 Feb |
Date Detail:
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Created Date: 1999-05-05 Completed Date: 1999-05-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 393-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of Washington, Harborview Medical Center, Seattle 98104, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Endometrial Neoplasms / pathology, ultrasonography* Endometrium / pathology* Female Humans Middle Aged Predictive Value of Tests Prospective Studies Sensitivity and Specificity Ultrasonography / methods Uterine Diseases / pathology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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