Document Detail

Prediction of arrhythmic events in patients following myocardial infarction.
MedLine Citation:
PMID:  2684459     Owner:  NLM     Status:  MEDLINE    
The value of techniques used to predict arrhythmic events (sudden cardiac death not preceded by reinfarction and spontaneous sustained ventricular tachycardia) after acute myocardial infarction is reviewed. A full clinical assessment allows the detection of patients with major infarction, present in the majority of those suffering arrhythmic events during follow-up. More sophisticated noninvasive tests, including Holter monitoring, and the high gain, signal averaged ECG, add prognostic accuracy to clinical assessment in patients with major infarction but are by themselves nonspecific. Noninvasive assessment of autonomic function from baroreceptor sensitivity analysis and heart rate variability measurement may also provide useful prognostic information. The results of programmed ventricular stimulation studies in patients with recent acute infarction have been contradictory, though many of the disagreements can be explained by methodological differences. At best this technique is highly invasive, and probably adds little to what can be discovered from a thorough noninvasive assessment. The treatment to be adopted in those judged to be at high risk remains to be established, and this may include nonpharmacological modalities such as the implantable defibrillator and surgical ablation as alternatives to drug therapy.
T R Cripps; A J Camm
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  12     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1989-12-27     Completed Date:  1989-12-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  661-5     Citation Subset:  IM    
National Heart Hospital, London, England.
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MeSH Terms
Arrhythmias, Cardiac / diagnosis*,  epidemiology,  etiology
Myocardial Infarction / complications,  mortality*,  physiopathology
Predictive Value of Tests
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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