Document Detail


Prediction of adverse neonatal outcomes in preeclampsia by absent or reversed end-diastolic flow velocity in the umbilical artery.
MedLine Citation:
PMID:  14691343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the independent contribution of absent or reversed end-diastolic umbilical artery Doppler flow (AREDF) in the prediction of subsequent adverse neonatal outcomes, we performed Doppler examinations on 270 preeclamptic women with a singleton pregnancy. The end-point variables were low Apgar scores and adverse neonatal outcomes (respiratory distress syndrome, intracranial hemorrhage, sepsis, seizures, jaundice, hypoglycemia, hypocalcemia, thrombocytopenia, polycythemia, and neonatal mortality). Stepwise logistic regression was used to control for gestational age, oligohydramnios, and fetal growth restriction. Infants with AREDF had an increased frequency of hypoglycemia (odds ratio=1.7) and polycythemia (odds ratio=1.7), whereas the remaining neonatal outcomes were explained by gestational age and growth restriction. Therefore, live-born infants of preeclamptic patients with AREDF velocities, independent of prematurity and growth restriction, are prone to hypoglycemia and polycythemia.
Authors:
Mekin Sezik; Görkem Tuncay; Elif Gül Yapar
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Publication Detail:
Type:  Journal Article     Date:  2003-12-19
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  57     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  2004  
Date Detail:
Created Date:  2004-01-30     Completed Date:  2004-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  109-13     Citation Subset:  IM    
Copyright Information:
Copyright 2004 S. Karger AG, Basel
Affiliation:
Department of Obstetrics and Gynecology, Süleyman Demirel University, School of Medicine, Isparta, Turkey. msezik@med.sdu.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity
Female
Gestational Age
Humans
Logistic Models
Pre-Eclampsia / complications*,  physiopathology
Predictive Value of Tests
Pregnancy
Pregnancy Outcome*
Rheology
Umbilical Arteries / physiology*

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