Document Detail

Predicting risks of preeclampsia and small for gestational age infant by uterine artery Doppler.
MedLine Citation:
PMID:  19003639     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the value of uterine artery Doppler as a screening test for preeclampsia and/or having a small-for-gestational-age (SGA) infant in healthy pregnant women.
METHODS: Color Doppler ultrasound was used to examine both uterine arteries in 400 healthy pregnant women at 24.8 +/- 2.0 (range, 22 to 28) weeks of gestation. The mean pulsatility index of both uterine arteries was calculated and the presence of an early diastolic notch in the waveform was noted.
RESULTS: Twenty-six (6.5%) of the 400 women developed preeclampsia and/or had an SGA infant. The optimal cutoff value for the mean pulsatility index in predicting preeclampsia and/or having an SGA infant was 0.857. When using a high mean pulsatility index and/or the presence of any early diastolic notch, the detection of preeclampsia and/or having SGA infant were a sensitivity of 76.9%, a specificity of 52.9%, a positive predictive value of 10.2%, and a negative predictive value of 97.1%, respectively.
CONCLUSION: Women with an abnormal uterine artery Doppler great a considerably higher risk for developing preeclampsia and/or having an SGA infant.
Vorapong Phupong; Thewin Dejthevaporn
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Hypertension in pregnancy     Volume:  27     ISSN:  1525-6065     ISO Abbreviation:  Hypertens Pregnancy     Publication Date:  2008  
Date Detail:
Created Date:  2008-11-12     Completed Date:  2009-02-17     Revised Date:  2014-07-23    
Medline Journal Info:
Nlm Unique ID:  9421297     Medline TA:  Hypertens Pregnancy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  387-95     Citation Subset:  IM    
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MeSH Terms
Fetal Growth Retardation / diagnosis*
Infant, Newborn
Infant, Small for Gestational Age
Mass Screening
Pre-Eclampsia / diagnosis*
Pregnancy Outcome
Prospective Studies
Pulsatile Flow*
Ultrasonography, Doppler, Color*
Uterus / blood supply*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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