| Predicting response to therapy in acute asthma. | |
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MedLine Citation:
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PMID: 19077703 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE OF REVIEW: To analyze the prediction of response of therapy into the context of acute adult asthma assessment in the emergency department (ED) setting. RECENT FINDINGS: Close monitoring of the patient's condition at presentation (static assessment) and response to treatment (dynamic assessment), including serial measurements of lung function, is an essential part of the acute asthma care in the ED. The severity of airflow obstruction cannot be accurately judged by patient's symptoms and physical examination alone. Accordingly, it is very important to use an objective measure of airway obstruction (spirometry or peak flow meter). Although spirometry can be performed in acutely ill ED asthmatics, measurement of peak expiratory flow, with values expressed as predicted normal values, represents an alternative if spirometry is not available. SUMMARY: Failure of initial therapy to improve expiratory flow predicts a more severe course and need for hospitalization. Although several score systems have been developed, different factors limit their applicability in the ED setting. Thus, peak expiratory flow rate measures at 15-60 min of treatment, joined with continuous monitoring of oxygen saturation may be the best ways to assess patients with acute asthma. |
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Authors:
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Gustavo J Rodrigo |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in pulmonary medicine Volume: 15 ISSN: 1531-6971 ISO Abbreviation: Curr Opin Pulm Med Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-16 Completed Date: 2009-02-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9503765 Medline TA: Curr Opin Pulm Med Country: United States |
Other Details:
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Languages: eng Pagination: 35-8 Citation Subset: IM |
Affiliation:
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Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay. gurodrig@adinet.com.uy |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Anti-Asthmatic Agents / therapeutic use* Asthma / drug therapy*, physiopathology Emergency Service, Hospital* Forced Expiratory Volume / physiology Humans Peak Expiratory Flow Rate / physiology Predictive Value of Tests Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Asthmatic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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