Document Detail


Predicting post-coronary bypass surgery atrial arrhythmias from the preoperative electrocardiogram.
MedLine Citation:
PMID:  11685166     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Atrial fibrillation (AF) after coronary artery bypass grafting (CABG) is a common occurrence and adds to the morbidity and cost associated with the procedure. Various therapies have been demonstrated to reduce the risk of post-CABG AF, but their use should be targeted to high-risk patients. The purpose of this study was to develop a prediction rule for post-CABG AF on the basis of patient age and the preoperative electrocardiogram (ECG). METHODS: The charts of 152 consecutive patients undergoing isolated CABG at one institution were reviewed and the preoperative ECG was analyzed with use of commercially available software. Logistic regression was performed and age-adjusted predictors of the primary end point, any post-CABG AF, were derived. The discriminatory values of the various models were compared by receiver-operating characteristic curves. RESULTS: Sixty-four patients (42.1%) had AF. Multivariable predictors were dichotomized on the basis of variable distribution, and a high-risk patient population was identified by age >65 years, PR interval >/=180 milliseconds (age-adjusted odds ratio [OR] 2.12, P =.05), and a P-wave duration in lead V1 >/=110 milliseconds (age-adjusted OR 2.30, P =.02). CONCLUSIONS: This study demonstrates that post-CABG AF can be predicted preoperatively from patient age and evidence of intra-atrial conduction delay on ECG. Such information can be used to guide prophylactic therapy.
Authors:
R Passman; J Beshai; B Pavri; S Kimmel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  142     ISSN:  1097-6744     ISO Abbreviation:  Am. Heart J.     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-10-30     Completed Date:  2002-01-08     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  806-10     Citation Subset:  AIM; IM    
Affiliation:
Feinberg Cardiovascular Research Institute and the Departments of Medicine and Preventive Medicine, Division of Cardiology, Northwestern University Medical School, Chicago, IL, USA. r-passman@northwestern.edu
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / epidemiology*,  etiology
Atrial Flutter / epidemiology*,  etiology
Coronary Artery Bypass / adverse effects*
Coronary Disease / surgery*
Electrocardiography / statistics & numerical data*
Humans
Postoperative Complications / epidemiology,  etiology
Probability

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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