| Predicting the outcome of newborns with gastroschisis. | |
| | |
MedLine Citation:
|
PMID: 19433170 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The objective of the study was to determine factors predicting outcome in newborns with gastroschisis. METHODS: A retrospective analysis of 155 consecutive cases admitted from 1 January 1990 to 31 December 2007 was performed. Prenatal ultrasound findings were available for 89 of 155 (57%) patients and were compared with final outcome. Both univariate and multiple regression analyses were used. RESULTS: All patients survived to discharge home. The primary outcome measure was length of stay. Multiple regression identified 4 factors associated with length of stay: (1) gestational age (P = .004), (2) nonelective silo (P < .001), (3) gastrointestinal (GI) complication (intestinal atresia, perforation, or resection) (P < .001), and (4) non-GI anomaly (P = .029). Non-GI anomalies occurred in 17 of 155 (11%) patients and tended to increase the risk of a nonelective silo or GI complication (59% vs 39%, P = .190). Dilated bowel (>10 mm) on prenatal ultrasound was associated with GI complications (22% vs 3%, P = .010). However, 78% of patients with dilated bowel on prenatal ultrasound did not have a GI complication. The absence of dilated bowel on prenatal ultrasound accurately predicted the absence of GI complications in 97% of cases. CONCLUSION: Prematurity, nonelective silo, GI complications, and non-GI anomalies predict the short-term outcome of newborns with gastroschisis. Prenatal ultrasound serves primarily to predict the absence of GI complications. |
| | |
Authors:
|
Nathaniel R Payne; Kathleen Pfleghaar; Barbara Assel; Aubrey Johnson; R Hampton Rich |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of pediatric surgery Volume: 44 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2009 May |
Date Detail:
|
Created Date: 2009-05-12 Completed Date: 2009-10-14 Revised Date: 2010-09-27 |
Medline Journal Info:
|
Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 918-23 Citation Subset: IM |
Affiliation:
|
Division of Neonatology, Children's Hospital and Clinics of Minnesota, Minneapolis, MN 55404, USA. rob.payne@childrensmn.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abnormalities, Multiple
/
epidemiology Adult Digestive System Abnormalities / epidemiology Dilatation, Pathologic / embryology, ultrasonography Female Gastroschisis / embryology, epidemiology, surgery*, ultrasonography Gestational Age Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases / epidemiology, surgery, ultrasonography Intensive Care Units, Neonatal / statistics & numerical data Length of Stay Male Maternal Age Minnesota / epidemiology Pregnancy Prognosis Retrospective Studies Risk Factors Ultrasonography, Prenatal* |
| Grant Support | |
ID/Acronym/Agency:
|
5 T-32 HD046377/HD/NICHD NIH HHS; T32 HD046377-04/HD/NICHD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Is timing everything? The influence of gestational age, birth weight, route, and intent of delivery ...
Next Document: The timing of enterostomy reversal after necrotizing enterocolitis.