Document Detail

Predicting outcome in high-risk newborns with a neonatal neurobehavioral assessment.
MedLine Citation:
PMID:  7524328     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Effective medical management and rehabilitation efforts in neonates at risk depend on early identification of underlying brain injury. The aim of this study was to determine the prognostic value of the Einstein Neonatal Neurobehavioral Assessment Scale (ENNAS) in high-risk neonates, and to compare its predictive validity at two stages in development (i.e., 1 and 3 years of age).
METHOD: Twenty-three healthy neonates (control group) and 51 high-risk neonates (high-risk group) were assessed at term and were followed longitudinally. At 1 and 3 years, subjects in both groups were evaluated in a blind fashion by a psychologist and a pediatric neurologist.
RESULTS: Developmental delays became more apparent as high-risk newborns matured; the percentage of subjects with an abnormal Griffiths general quotient increased from 1 year (13.7%) to 3 years (39%). Analysis revealed that a normal neonatal performance on the ENNAS in high-risk subjects accurately predicted a favorable outcome at 1 year and 3 years of age. Although an abnormal ENNAS was not consistently associated with a poor outcome, the positive predictive value improved markedly from 1 year to 3 years of age.
CONCLUSION: The findings indicate that a normal neonatal neurobehavioral assessment is reassuring, as most of these children are free of neurodevelopmental sequelae at 3 years of age. For many persons, the ENNAS may provide early evidence of a pattern of brain injury that is manifested only as the child is challenged by more complex skill acquisition such as language, memory, and perceptual-motor tasks. The ability of this assessment to predict behavioral and academic skills at school age remains to be determined. Early identification of developmental deficits enables occupational therapists to direct infants to appropriate early intervention programs, thus optimizing their functional potential.
A Majnemer; B Rosenblatt; P Riley
Related Documents :
19188928 - Intra-rater agreement of the anorectal exam and classification of injury severity in ch...
9562908 - Prediction of employment outcome one to three years following traumatic brain injury (t...
12612618 - Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subj...
19833158 - Age-dependent response of ccaat/enhancer binding proteins following traumatic brain inj...
3427328 - Urinary risk factors in calcium oxalate stone disease: comparison of men and women.
9523208 - Syndrome x: is it for real?
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of occupational therapy : official publication of the American Occupational Therapy Association     Volume:  48     ISSN:  0272-9490     ISO Abbreviation:  Am J Occup Ther     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-11-22     Completed Date:  1994-11-22     Revised Date:  2012-08-27    
Medline Journal Info:
Nlm Unique ID:  7705978     Medline TA:  Am J Occup Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  723-32     Citation Subset:  IM    
School of Physical and Occupational Therapy, McGill University, Montreal, Quebec.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brain Damage, Chronic / diagnosis*
Developmental Disabilities / diagnosis*
Infant, Newborn
Infant, Premature*
Neurologic Examination*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Somatosensory processing abilities of very low-birth weight infants at school age.
Next Document:  An immunohistochemical study of tissue transglutaminase in gliomas with reference to their cell dyin...