| Predicting longitudinal trajectories of health probabilities with random-effects multinomial logit regression. | |
| | |
MedLine Citation:
|
PMID: 22825754 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Researchers often encounter longitudinal health data characterized with three or more ordinal or nominal categories. Random-effects multinomial logit models are generally applied to account for potential lack of independence inherent in such clustered data. When parameter estimates are used to describe longitudinal processes, however, random effects, both between and within individuals, need to be retransformed for correctly predicting outcome probabilities. This study attempts to go beyond existing work by developing a retransformation method that derives longitudinal growth trajectories of unbiased health probabilities. We estimated variances of the predicted probabilities by using the delta method. Additionally, we transformed the covariates' regression coefficients on the multinomial logit function, not substantively meaningful, to the conditional effects on the predicted probabilities. The empirical illustration uses the longitudinal data from the Asset and Health Dynamics among the Oldest Old. Our analysis compared three sets of the predicted probabilities of three health states at six time points, obtained from, respectively, the retransformation method, the best linear unbiased prediction, and the fixed-effects approach. The results demonstrate that neglect of retransforming random errors in the random-effects multinomial logit model results in severely biased longitudinal trajectories of health probabilities as well as overestimated effects of covariates on the probabilities. Copyright © 2012 John Wiley & Sons, Ltd. |
| | |
Authors:
|
Xian Liu; Charles C Engel |
Related Documents
:
|
22282004 - Psychometric properties of the questionnaire of sociocultural influences on the aesthet... 22373144 - Integrating binary traits with quantitative phenotypes for association mapping of multi... 22246694 - A fibrocontractive mechanochemical model of dermal wound closure incorporating realisti... 22375114 - A selective review of multimodal fusion methods in schizophrenia. 22282004 - Psychometric properties of the questionnaire of sociocultural influences on the aesthet... 22373144 - Integrating binary traits with quantitative phenotypes for association mapping of multi... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-7-24 |
Journal Detail:
|
Title: Statistics in medicine Volume: - ISSN: 1097-0258 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-7-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8215016 Medline TA: Stat Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 John Wiley & Sons, Ltd. |
Affiliation:
|
Deployment Health Clinical Center, Walter Reed National Military Medical Center, Bethesda, MD, 20889, U.S.A.; Department of Psychiatry, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, U.S.A.. xian.liu@usuhs.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mous...
Next Document: Superficial venous thrombosis : A review.