Document Detail

Predicting fetal death by measuring oestrogen:creatinine ratios on early morning samples of urine.
MedLine Citation:
PMID:  922336     Owner:  NLM     Status:  MEDLINE    
Total oestrogens were measured, on a creatinine basis, by a fully automated method in 75 000 early morning specimens of urine from 5429 women. Among the 5241 pregnancies in which the oestrogen:creatinine ratio was normal there were 11 fetal deaths (0-21%). But there were 57 fetal deaths (30-3%) among 188 patients with ratios below the fifth centile. When delivery took place before the ratio decrease to below the fifth centile a live baby was born in every one of 59 pregnancies. Apart from its effectiveness in predicting fetal death, the test has a high degree of precision and can be performed swiftly, and cheaply. For these reasons the assessment of fetoplacental function by measuring the urinary:creatinine ratio could become a convenient and inexpensive part of antenatal care that could be extended to every pregnant woman without making many further demands on obstetricians' time.
L G Rao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  2     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  874-6     Citation Subset:  AIM; IM    
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MeSH Terms
Creatinine / urine*
Estrogens / urine*
Fetal Death*
Fetal Viability
Placental Function Tests / methods*
Pregnancy Trimester, Third
Reg. No./Substance:
0/Estrogens; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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