Document Detail


Predicting clinical outcomes using baseline and follow-up laboratory data from the hepatitis C long-term treatment against cirrhosis trial.
MedLine Citation:
PMID:  22045670     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: Both the baseline value and the rapidity in change of the value of routine laboratory variables were shown to be important in predicting clinical outcomes in patients with advanced chronic hepatitis C.
Authors:
Marc G Ghany; Hae-Young Kim; Anne Stoddard; Elizabeth C Wright; Leonard B Seeff; Anna S F Lok;
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  54     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-02     Completed Date:  2012-01-09     Revised Date:  2013-07-25    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1527-37     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Association for the Study of Liver Diseases.
Affiliation:
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-1800, USA. marcg@intra.niddk.nih.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Alanine Transaminase / blood
Antiviral Agents / therapeutic use*
Aspartate Aminotransferases / blood
Bilirubin / blood
Biological Markers / blood
Databases, Factual / statistics & numerical data
Disease Progression
Female
Follow-Up Studies
Hepatitis C, Chronic / drug therapy*,  mortality*,  surgery
Humans
Liver Cirrhosis / mortality*,  surgery,  virology*
Liver Transplantation / statistics & numerical data
Male
Middle Aged
Multivariate Analysis
Platelet Count
Predictive Value of Tests
Randomized Controlled Trials as Topic
Risk Factors
Serum Albumin / metabolism
Grant Support
ID/Acronym/Agency:
1 UL1 RR 025780-01/RR/NCRR NIH HHS; 1 UL1 RR024982-01/RR/NCRR NIH HHS; 1 UL1 RR024986/RR/NCRR NIH HHS; 1 UL1 RR025758-01/RR/NCRR NIH HHS; M01RR-00042/RR/NCRR NIH HHS; M01RR-00043/RR/NCRR NIH HHS; M01RR-00051/RR/NCRR NIH HHS; M01RR-00065/RR/NCRR NIH HHS; M01RR-00633/RR/NCRR NIH HHS; M01RR-00827/RR/NCRR NIH HHS; M01RR-01066/RR/NCRR NIH HHS; M01RR-06192/RR/NCRR NIH HHS; N01-DK-9-2318/DK/NIDDK NIH HHS; N01-DK-9-2319/DK/NIDDK NIH HHS; N01-DK-9-2320/DK/NIDDK NIH HHS; N01-DK-9-2321/DK/NIDDK NIH HHS; N01-DK-9-2322/DK/NIDDK NIH HHS; N01-DK-9-2323/DK/NIDDK NIH HHS; N01-DK-9-2324/DK/NIDDK NIH HHS; N01-DK-9-2325/DK/NIDDK NIH HHS; N01-DK-9-2326/DK/NIDDK NIH HHS; N01-DK-9-2327/DK/NIDDK NIH HHS; N01-DK-9-2328/DK/NIDDK NIH HHS; ZIA DK075009-07/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Antiviral Agents; 0/Biological Markers; 0/Serum Albumin; 635-65-4/Bilirubin; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase
Investigator
Investigator/Affiliation:
Gyongyi Szabo / ; Barbara F Banner / ; Maureen Cormier / ; Donna Giansiracusa / ; Herbert L Bonkovsky / ; Gloria Borders / ; Michelle Kelley / ; Adrian M Di Bisceglie / ; Bruce Bacon / ; Brent Neuschwander-Tetri / ; Elizabeth M Brunt / ; Debra King / ; Jules L Dienstag / ; Raymond T Chung / ; Andrea E Reid / ; Atul K Bhan / ; Wallis A Molchen / ; David P Lundmark / ; Gregory T Everson / ; Thomas Trouillot / ; Marcelo Kugelmas / ; S Russell Nash / ; Jennifer DeSanto / ; Carol McKinley / ; Timothy R Morgan / ; John C Hoefs / ; John R Craig / ; M Mazen Jamal / ; Muhammad Sheikh / ; Choon Park / ; William M Lee / ; Thomas E Rogers / ; Peter F Malet / ; Janel Shelton / ; Nicole Crowder / ; Rivka Elbein / ; Nancy Liston / ; Karen L Lindsay / ; Sugantha Govindarajan / ; Carol B Jones / ; Susan L Milstein / ; Robert J Fontana / ; Joel K Greenson / ; Pamela A Richtmyer / ; R Tess Bonham / ; Mitchell L Shiffman / ; Richard K Sterling / ; Melissa J Contos / ; A Scott Mills / ; Charlotte Hofmann / ; Paula Smith / ; T Jake Liang / ; David Kleiner / ; Yoon Park / ; Elenita Rivera / ; Vanessa Haynes-Williams / ; James E Everhart / ; Patricia R Robuck / ; Jay H Hoofnagle / ; Chihiro Morishima / ; David R Gretch / ; Minjun Chung Apodaca / ; Rohit Shankar / ; Natalia Antonov / ; Kristin K Snow / ; Anne M Stoddard / ; Teresa M Curto / ; Zachary D Goodman / ; Fanny Monge / ; Michelle Parks / ; Gary L Davis / ; Guadalupe Garcia-Tsao / ; Michael Kutner / ; Stanley M Lemon / ; Robert P Perrillo /
Comments/Corrections

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