Document Detail

Predicting pregnancy in HIV-1-discordant couples.
MedLine Citation:
PMID:  20544384     Owner:  NLM     Status:  MEDLINE    
This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy was 9.7%. Pregnancy rates did not differ significantly between HIV-1-infected and uninfected women (HR = 1.46). The majority of pregnancies occurred among women < 30 years old reporting a desire for future children (1-year incidence 22.2%). Pregnancy rates may be high among discordant couples, indicating desire for children may override concerns of HIV-1 transmission and increase unprotected sex, and highlighting the need to make conception safer.
Brandon L Guthrie; Robert Y Choi; Rose Bosire; James N Kiarie; Romel D Mackelprang; Anne Gatuguta; Grace C John-Stewart; Carey Farquhar
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  AIDS and behavior     Volume:  14     ISSN:  1573-3254     ISO Abbreviation:  AIDS Behav     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-24     Completed Date:  2010-12-20     Revised Date:  2013-05-17    
Medline Journal Info:
Nlm Unique ID:  9712133     Medline TA:  AIDS Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1066-71     Citation Subset:  IM    
Department of Epidemiology, University of Washington, Seattle, WA 98104-2499, USA.
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MeSH Terms
Age Distribution
Cohort Studies
Follow-Up Studies
HIV Infections / epidemiology*,  psychology,  transmission
HIV Seronegativity
HIV Seropositivity / epidemiology*,  psychology,  transmission
HIV-1 / immunology
Kenya / epidemiology
Pregnancy Rate*
Risk Factors
Spouses / statistics & numerical data
Young Adult
Grant Support
D43 TW000007/TW/FIC NIH HHS; K01 TW008406-02/TW/FIC NIH HHS; K01 TW008406-03/TW/FIC NIH HHS; K24 HD054314/HD/NICHD NIH HHS; K24 HD054314-04/HD/NICHD NIH HHS; K24 HD054314-05/HD/NICHD NIH HHS; L30 AI097101/AI/NIAID NIH HHS; P30 AI027757/AI/NIAID NIH HHS; R01 AI068431/AI/NIAID NIH HHS; R01 AI068431/AI/NIAID NIH HHS; T32 AI007140/AI/NIAID NIH HHS; T32 AI007140-34/AI/NIAID NIH HHS; T32 AI07140/AI/NIAID NIH HHS; TL1 RR025016-01/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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