| Predicting pregnancy in HIV-1-discordant couples. | |
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MedLine Citation:
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PMID: 20544384 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy was 9.7%. Pregnancy rates did not differ significantly between HIV-1-infected and uninfected women (HR = 1.46). The majority of pregnancies occurred among women < 30 years old reporting a desire for future children (1-year incidence 22.2%). Pregnancy rates may be high among discordant couples, indicating desire for children may override concerns of HIV-1 transmission and increase unprotected sex, and highlighting the need to make conception safer. |
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Authors:
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Brandon L Guthrie; Robert Y Choi; Rose Bosire; James N Kiarie; Romel D Mackelprang; Anne Gatuguta; Grace C John-Stewart; Carey Farquhar |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: AIDS and behavior Volume: 14 ISSN: 1573-3254 ISO Abbreviation: AIDS Behav Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-24 Completed Date: 2010-12-20 Revised Date: 2013-05-01 |
Medline Journal Info:
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Nlm Unique ID: 9712133 Medline TA: AIDS Behav Country: United States |
Other Details:
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Languages: eng Pagination: 1066-71 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, University of Washington, Seattle, WA 98104-2499, USA. brguth@u.washington.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Cohort Studies Female Follow-Up Studies Forecasting HIV Infections / epidemiology*, psychology, transmission HIV Seronegativity HIV Seropositivity / epidemiology*, psychology, transmission HIV-1 / immunology Humans Incidence Kenya / epidemiology Male Pregnancy Pregnancy Rate* Reproduction* Risk Factors Spouses / statistics & numerical data Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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K01 TW008406-02/TW/FIC NIH HHS; K01 TW008406-03/TW/FIC NIH HHS; K24 HD054314/HD/NICHD NIH HHS; K24 HD054314-04/HD/NICHD NIH HHS; K24 HD054314-05/HD/NICHD NIH HHS; L30 AI097101/AI/NIAID NIH HHS; P30 AI027757/AI/NIAID NIH HHS; R01 AI068431/AI/NIAID NIH HHS; T32 AI007140/AI/NIAID NIH HHS; T32 AI007140-34/AI/NIAID NIH HHS; T32 AI07140/AI/NIAID NIH HHS; TL1 RR025016-01/RR/NCRR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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