| Prediagnostic serum hormones and the risk of prostate cancer. | |
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MedLine Citation:
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PMID: 3370644 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum samples were obtained from 6860 men during their study examination from 1971 to 1975. After a surveillance period of about 14 years, 98 incident cases of prostate cancer were identified. Their stored sera and that of 98 matched controls from the study population were tested for the following: testosterone, dihydrotestosterone, estrone, estradiol, and sex hormone globulin. There was a suggestion that serum dihydrotestosterone levels were lower and the testosterone/dihydrotestosterone ratios were higher in the prostate cancer cases compared with their controls. However, none of these associations or that of the other hormones was strongly significant. Further work is needed to clarify the relationship between sex hormones and prostate cancer risk. |
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Authors:
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A Nomura; L K Heilbrun; G N Stemmermann; H L Judd |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Cancer research Volume: 48 ISSN: 0008-5472 ISO Abbreviation: Cancer Res. Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1988-06-29 Completed Date: 1988-06-29 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2984705R Medline TA: Cancer Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 3515-7 Citation Subset: IM |
Affiliation:
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Japan-Hawaii Cancer Study, Kuakini Medical Center, Honolulu 96817. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Estrogens
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blood Gonadal Steroid Hormones / blood* Humans Male Prostatic Neoplasms / blood* Risk Testosterone / blood |
| Grant Support | |
ID/Acronym/Agency:
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R01 CA 33644/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 0/Gonadal Steroid Hormones; 58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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