| Precuneal activity during encoding in veterans with posttraumatic stress disorder. | |
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MedLine Citation:
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PMID: 18037028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Impaired attention and memory are symptoms frequently associated with posttraumatic stress disorder (PTSD). Previous studies have identified fronto-temporal alterations during encoding in patients with PTSD. We examine the role of the precuneus (located in the posteromedial parietal lobe) that is known to play a role in memory, but has largely been neglected in PTSD research. Male veterans with and without PTSD (n=12 per group) were subjected to fMRI during encoding of 12 neutral, non-trauma related word pairs. The precuneus was less activated in veterans with PTSD, which correlated significantly with the severity of PTSD. Like fronto-temporal regions the precuneus is differentially activated during memory formation in veterans with PTSD. |
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Authors:
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Elbert Geuze; Eric Vermetten; Carien S de Kloet; Herman G M Westenberg |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Progress in brain research Volume: 167 ISSN: 0079-6123 ISO Abbreviation: Prog. Brain Res. Publication Date: 2008 |
Date Detail:
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Created Date: 2007-11-26 Completed Date: 2008-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376441 Medline TA: Prog Brain Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 293-7 Citation Subset: IM |
Affiliation:
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Department of Military Psychiatry, Central Military Hospital, Ministry of Defense, Utrecht, The Netherlands. s.g.geuze@umcutrecht.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Magnetic Resonance Imaging Male Parietal Lobe / physiopathology* Psychiatric Status Rating Scales Stress Disorders, Post-Traumatic / physiopathology*, psychology Veterans* |
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