| Precontrast and postcontrast susceptibility-weighted imaging in the assessment of intracranial brain neoplasms at 1.5 T. | |
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MedLine Citation:
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PMID: 20512548 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The goal of this study was to estimate pre- and post-gadolinium-enhanced high-spatial resolution susceptibility-weighted imaging (SWI) in patients with brain neoplasms. MATERIALS AND METHODS: A total of 17 patients (8 women, 9 men) with brain neoplasms participated in this study. In addition to conventional magnetic resonance imaging, pre- and post-gadolinium-enhanced SWI was performed. The contrast-to-noise ratio (CNR) and major diameters of the brain tumor were measured for quantitative analyses, and intratumoral susceptibility signal intensity (ITSS) was graded for semiquantitative analysis. RESULTS: Both bright and dark enhancement were observed at the pathological lesion on postcontrast SWI. Some postcontrast SWI results suggested leakage of contrast material due to breakdown of the blood-brain barrier. There were no statistical differences (Student's t-test) between postcontrast SWI and three-dimensional (3D) T1-weighted images regarding the major diameters of the brain tumors. CNR of postcontrast 3D T1-weighted images was statistically superior to that of postcontrast SW images (P < 0.01, Wilcoxon signed-rank test). Malignant tumors tended to have a higher ITSS score. CONCLUSION: SWI clearly visualized the architecture of brain neoplasms. This imaging technique may be useful for evaluating tumor characterization in clinical use. |
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Authors:
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Masaaki Hori; Keiichi Ishigame; Hiroyuki Kabasawa; Hiroshi Kumagai; Satoshi Ikenaga; Nobuyuki Shiraga; Shigeki Aoki; Tsutomu Araki |
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Publication Detail:
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Type: Journal Article Date: 2010-05-29 |
Journal Detail:
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Title: Japanese journal of radiology Volume: 28 ISSN: 1867-108X ISO Abbreviation: Jpn J Radiol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-31 Completed Date: 2010-09-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101490689 Medline TA: Jpn J Radiol Country: Japan |
Other Details:
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Languages: eng Pagination: 299-304 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Yamanashi, 1110 Shimogato, Chuo, 409-3898, Japan. masahori@yamanashi.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain Neoplasms
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pathology* Contrast Media Female Gadolinium DTPA / diagnostic use Humans Image Enhancement / methods Imaging, Three-Dimensional Magnetic Resonance Imaging / methods* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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