| Preconditioning and protection against ischaemia-reperfusion in non-cardiac organs: a place for volatile anaesthetics? | |
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MedLine Citation:
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PMID: 17555610 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is an increasing body of evidence that volatile anaesthetics protect myocardium against ischaemic insult by a mechanism termed 'anaesthetic preconditioning'. Anaesthetic preconditioning and ischaemic preconditioning share several common mechanisms of action. Since ischaemic preconditioning has been demonstrated in organs other than the heart, anaesthetic preconditioning might also apply in these organs and have significant clinical applications in surgical procedures carrying a high risk of ischaemia-reperfusion injury. After a brief review on myocardial preconditioning, experimental and clinical data on preconditioning in non-cardiac tissues will be presented. Potential benefits of anaesthetic preconditioning during non-cardiac surgery will be addressed. |
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Authors:
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G Minguet; J Joris; M Lamy |
Publication Detail:
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Type: Journal Article; Review Date: 2007-06-07 |
Journal Detail:
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Title: European journal of anaesthesiology Volume: 24 ISSN: 0265-0215 ISO Abbreviation: Eur J Anaesthesiol Publication Date: 2007 Sep |
Date Detail:
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Created Date: 2007-08-09 Completed Date: 2007-12-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8411711 Medline TA: Eur J Anaesthesiol Country: England |
Other Details:
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Languages: eng Pagination: 733-45 Citation Subset: IM |
Affiliation:
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University of Liège, Department of Anaesthesia and Intensive Care Medicine, Belgium. gminguet@chu.ulg.ac.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthetics, Inhalation
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pharmacology* Animals Humans Ischemic Preconditioning / methods* Ischemic Preconditioning, Myocardial / methods Mice Reperfusion Injury / prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Inhalation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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