| Preconditioning in humans. | |
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MedLine Citation:
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PMID: 17508280 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Brief ischemia to the myocardium initiates a cascade of biochemical events in cardiac myocytes that protects the heart muscle during subsequent ischemic insults. This phenomenon is called ischemic preconditioning. If an acute myocardial infarction is preceded by preinfarction angina, it results in smaller infarction size, fewer cardiac arrhythmias, and better-left ventricular function. During coronary intervention, brief balloon inflation protects the heart during subsequent inflations. Patients vary in the degree of preconditioning and those patients who have the ability to demonstrate a significant preconditioning effect will have lesser incidence of subsequent cardiac events. Preconditioning protects the myocardium during coronary artery bypass surgery, particularly in the off-pump procedure, yet the thoracic surgery community has not universally adopted this technique. |
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Authors:
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Shereif H Rezkalla; Robert A Kloner |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Heart failure reviews Volume: 12 ISSN: 1382-4147 ISO Abbreviation: Heart Fail Rev Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-07-19 Completed Date: 2007-11-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612481 Medline TA: Heart Fail Rev Country: United States |
Other Details:
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Languages: eng Pagination: 201-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Marshfield Clinic, 1000 North Oak Avenue, Marshfield, WI 54449, USA. rezkalla.shereif@marshfieldclinic.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Angioplasty, Transluminal, Percutaneous Coronary Coronary Artery Bypass / methods* Humans Ischemic Preconditioning, Myocardial* Myocardial Infarction / complications, prevention & control* Myocardial Ischemia / prevention & control* Myocardium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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