Document Detail

Preconception mental health predicts pregnancy complications and adverse birth outcomes: a national population-based study.
MedLine Citation:
PMID:  22124801     Owner:  NLM     Status:  MEDLINE    
Pregnancy complications and poor birth outcomes can affect the survival and long-term health of children. The preconception period represents an opportunity to intervene and improve outcomes; however little is known about women's mental health prior to pregnancy as a predictor of such outcomes. We sought to determine if and to what extent women's preconception mental health status impacted subsequent pregnancy complications, non-live birth, and birth weight using a nationally representative, population-based sample. We used pooled 1996-2006 data from the nationally-representative Medical Expenditure Panel Survey (MEPS). Poor preconception mental health was defined as women's global mental health rating of "fair" or "poor" before conception. Logistic regression was used to assess the association between preconception mental health and pregnancy complications, non-live birth, and having a low birth weight baby within the follow up period. Poor preconception mental health was associated with increased odds of experiencing any pregnancy complication (AOR 1.40, 95% CI: 1.02-1.92), having a non-live birth (AOR 1.48, 95% CI: 0.96-2.27), and having a low birth weight baby (AOR 1.99, 95% CI: 1.00-3.98), all controlling for maternal age, race/ethnicity, marital status, education, health insurance status, income, and number of children in the household. Significant racial and ethnic disparities exist for pregnancy complications and non-live births, but not for low birth weight. Women's preconception mental health is a modifiable risk factor that stands to reduce the incidence of adverse pregnancy complications and birth outcomes.
Whitney P Witt; Lauren E Wisk; Erika R Cheng; John M Hampton; Erika W Hagen
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Maternal and child health journal     Volume:  16     ISSN:  1573-6628     ISO Abbreviation:  Matern Child Health J     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-17     Completed Date:  2012-12-03     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  9715672     Medline TA:  Matern Child Health J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1525-41     Citation Subset:  IM    
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MeSH Terms
Birth Weight
Health Status
Health Status Disparities
Infant, Newborn
Logistic Models
Maternal Age
Maternal Behavior*
Mental Disorders / epidemiology*
Mental Health
Multivariate Analysis
Odds Ratio
Population Surveillance
Preconception Care*
Pregnancy Complications / epidemiology,  psychology*
Pregnancy Outcome / epidemiology,  psychology*
Risk Factors
Socioeconomic Factors
United States / epidemiology
Young Adult
Grant Support
HS000083/HS/AHRQ HHS; HS000083-12/HS/AHRQ HHS; T32 HD049302/HD/NICHD NIH HHS; T32 HD049302/HD/NICHD NIH HHS; T32 HS00083/HS/AHRQ HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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