| Prebiotics and lipid metabolism. | |
| | |
MedLine Citation:
|
PMID: 11790964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Prebiotics are defined as nondigestible food ingredients that beneficially affect the host by selectively stimulating the growth or the activity of one or a limited number of bacteria (bifidobacteria, lactobacilli) in the colon. Dietary fructans are nutritionally interesting oligosaccharides that strictly conform to the definition of prebiotics and (in view of experimental studies in animals and of less numerous studies in humans) exhibit interesting serum or hepatic lipid lowering properties. Other nondigestible/fermentable nutrients, which also modulate intestinal flora activity, exhibit cholesterol or triglyceride lowering effects. Are changes in intestinal bacterial flora composition or fermentation activity responsible for those effects? What is the future of prebiotics in the nutritional control of lipidaemia and cardiovascular disease risk in humans? Those questions only receive partial response in the present review because studies of the systemic effects of prebiotics are still in their infancy, and require fundamental research devoted to elucidating the biochemical and physiological events that allow prebiotics to exert systemic effects on lipid metabolism. |
| | |
Authors:
|
Nathalie M Delzenne; Christine M Williams |
Related Documents
:
|
19617514 - Dietary mannan oligosaccharide supplementation modulates intestinal microbial ecology a... 16107594 - Dietary supplementation with orotate and uracil increases adaptive growth of jejunal mu... 7986244 - Effects of dietary fat levels on the absorption and tissue accumulation of probucol in ... 2752034 - The stimulation of glucose absorption and metabolism in rat jejunum by bradykinin: depe... 3121554 - Effects of high fat diet on fecal contents of bile acids in rats. 19720794 - Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin actio... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Current opinion in lipidology Volume: 13 ISSN: 0957-9672 ISO Abbreviation: Curr. Opin. Lipidol. Publication Date: 2002 Feb |
Date Detail:
|
Created Date: 2002-01-15 Completed Date: 2002-06-14 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9010000 Medline TA: Curr Opin Lipidol Country: England |
Other Details:
|
Languages: eng Pagination: 61-7 Citation Subset: IM |
Affiliation:
|
UCL-Université Catholique de Louvain, School of Pharmacy, Brussels, Belgium. Delzenne@pmnt.ucl.ac.be |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bifidobacterium / physiology Cardiovascular Diseases / prevention & control Colon / drug effects, microbiology Fermentation / drug effects Fructans / pharmacology, therapeutic use Humans Hyperlipidemias / prevention & control Lactobacillus / physiology Lipid Metabolism* Lipids / antagonists & inhibitors, blood Oligosaccharides / pharmacology, therapeutic use Probiotics / pharmacology*, therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Fructans; 0/Lipids; 0/Oligosaccharides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulatin...
Next Document: National cholesterol education program keeps a priority on lifestyle modification to decrease cardio...